1例流感疫苗接种后发生伊文斯综合征的病例。
A case of Evans' syndrome following influenza vaccine.
作者信息
Shlamovitz Gil Z, Johar Sandeep
机构信息
The Section of Emergency Medicine, Ben Taub General Hospital, Baylor College of Medicine, Houston, TX 77030, USA.
出版信息
J Emerg Med. 2013 Feb;44(2):e149-51. doi: 10.1016/j.jemermed.2012.01.060. Epub 2012 Jul 15.
BACKGROUND
Evans' syndrome is an uncommon condition defined by the combination (either simultaneously or sequentially) of immune thrombocytopenia purpura and autoimmune hemolytic anemia with a positive direct antiglobulin test in the absence of known underlying etiology.
OBJECTIVES
We present a case of Evans' syndrome following influenza vaccination.
CASE REPORT
A 50-year-old man with no prior medical history developed Evans' syndrome 4 days after receiving influenza immunization. The patient improved following treatment with oral prednisone and intravenous immunoglobulin.
CONCLUSION
Influenza vaccine is one of the most commonly used vaccines worldwide, with millions of people being vaccinated annually. Despite its wide use, only sparse information has been published concerning any hematological effects of this vaccine. The rarity of such effects supports the safety of using this vaccine.
背景
伊文氏综合征是一种罕见疾病，定义为免疫性血小板减少性紫癜和自身免疫性溶血性贫血同时或先后出现，且直接抗球蛋白试验呈阳性，同时不存在已知潜在病因。
目的
我们报告一例流感疫苗接种后发生伊文氏综合征的病例。
病例报告
一名既往无病史的50岁男性在接种流感疫苗4天后发生伊文氏综合征。患者经口服泼尼松和静脉注射免疫球蛋白治疗后病情好转。
结论
流感疫苗是全球最常用的疫苗之一，每年有数以百万计的人接种。尽管其使用广泛，但关于该疫苗血液学影响的公开信息却很少。此类影响的罕见性支持了使用该疫苗的安全性。
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