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一名未治疗幽门螺杆菌感染患者接种流感疫苗后发生急性免疫性血小板减少症

Acute Immune Thrombocytopenia Following Influenza Vaccination in a Patient With Untreated Helicobacter pylori Infection.

作者信息

Asiimwe Edgar, Kahlon Kanwarpal S

机构信息

Internal Medicine, University of California Los Angeles, Los Angeles, USA.

Hematology and Oncology, University of California Los Angeles, Los Angeles, USA.

出版信息

Cureus. 2023 Aug 22;15(8):e43946. doi: 10.7759/cureus.43946. eCollection 2023 Aug.

Abstract

A 70-year-old man with previously normal comprehensive blood counts (CBCs) was referred to our hospital for acute thrombocytopenia. Following a negative workup for secondary causes, we diagnosed immune thrombocytopenia (ITP). Aside from the influenza vaccine administered six days before presentation, there was no discernable precipitant on history. His only risk factor for ITP was untreated ​​​​​​ diagnosed over two months prior. With treatment, the patient's platelets normalized within three days. ITP following influenza vaccination has been documented in the literature and reported to regulatory bodies. Our case indicates that individuals with untreated infection might be particularly vulnerable to such occurrences.

摘要

一名70岁男性,既往全血细胞计数(CBC)正常,因急性血小板减少症转诊至我院。在对继发原因进行检查结果为阴性后,我们诊断为免疫性血小板减少症(ITP)。除了在就诊前六天接种的流感疫苗外,病史中没有可识别的诱发因素。他患ITP的唯一风险因素是两个多月前诊断出的感染未得到治疗。经过治疗,患者的血小板在三天内恢复正常。流感疫苗接种后发生ITP已在文献中有所记载,并已上报监管机构。我们的病例表明,未治疗感染的个体可能特别容易发生此类情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/035a/10513953/344aba51f92e/cureus-0015-00000043946-i01.jpg

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