咖啡烘焙厂空气中含内毒素的粉尘暴露工人的呼吸道炎症。
Respiratory inflammation among workers exposed to airborne dust with endotoxins in a coffee curing factory.
机构信息
Department of Public Health and Primary Health Care and Centre for International Health, University of Bergen, Bergen, Norway.
出版信息
J Occup Environ Med. 2012 Jul;54(7):847-50. doi: 10.1097/JOM.0b013e318250ca24.
OBJECTIVE
To study dust exposure and inflammatory reactions in the respiratory tract among coffee curing workers in Tanzania.
METHODS
A cross-sectional study was conducted in a Tanzanian coffee curing factory. Coffee workers (n = 15) were compared with unexposed controls (n = 18); all workers were nonsmokers. Exhaled nitric oxide was examined using an electrochemistry-based NIOX MINO device. Personal air samples were analyzed for total dust and endotoxins, using gravimetric analysis and the chromogenic Limulus amebocyte lysate endpoint assay, respectively.
RESULTS
Total dust levels ranged from 0.2 to 27.9 mg/m, and endotoxin levels ranged from 42 to 75,083 endotoxin units/m. Concentrations of exhaled nitric oxide, analyzed by linear regression and adjusted for age (β = 0.57; 95% confidence interval, 0.08 to 1.06; P = 0.02), was higher among coffee workers than among the control group.
CONCLUSION
The results indicate a relationship between the coffee dust and signs of respiratory inflammation.
目的
研究坦桑尼亚咖啡烘焙工人的粉尘暴露与呼吸道炎症反应。
方法
在坦桑尼亚的一家咖啡烘焙厂进行了一项横断面研究。将 15 名咖啡工人与未暴露的对照组（n = 18）进行比较；所有工人均为不吸烟者。使用基于电化学的 NIOX MINO 设备检测呼出气一氧化氮。使用重量分析法和显色鲎阿米巴细胞溶解物终点测定法分别分析个人空气样本中的总粉尘和内毒素。
结果
总粉尘水平范围为 0.2 至 27.9mg/m，内毒素水平范围为 42 至 75083 内毒素单位/m。通过线性回归分析，并校正年龄因素（β=0.57；95%置信区间，0.08 至 1.06；P=0.02），发现呼出气一氧化氮的浓度在咖啡工人中高于对照组。
结论
结果表明咖啡粉尘与呼吸道炎症的迹象之间存在关系。
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