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牙龈低度恶性肌纤维母细胞肉瘤

Low-grade myofibroblastic sarcoma of the gingiva.

作者信息

Montebugnoli L, Venturi M, Gissi D B, Flamminio F, Foschini M P

机构信息

Department of Oral Science, University of Bologna, Bologna, Italy.

出版信息

BMJ Case Rep. 2010 Nov 23;2010:bcr0720103166. doi: 10.1136/bcr.07.2010.3166.

Abstract

Low-grade myofibroblastic sarcoma is a malignant tumour from myofibroblasts, which has only recently become clearly defined. It represents a rare entity developing in the soft tissues of the head and neck. About 20 cases have been reported in the oral cavity, especially in the tongue and bone, while gingiva as the primary site has been described only once to date. Diagnostic methods include histology and immunohistochemistry. The present report concerns a case of a 37-year-old man who presented with a persistent gingival ulcerated swelling that was interpreted for a long time as a gingival epulis. A low-grade myofibrosarcoma was diagnosed and the patient underwent a segmental osteotomy of the mandibular symphisys for complete excision. There was no sign of recurrence or metastatic disease during the 18-month postoperative period.

摘要

低度恶性肌成纤维细胞肉瘤是一种源自肌成纤维细胞的恶性肿瘤,直到最近才得到明确界定。它是一种罕见的肿瘤,发生于头颈部软组织。口腔内约报告了20例,尤其是舌部和骨部,而牙龈作为原发部位迄今为止仅被描述过1次。诊断方法包括组织学和免疫组织化学。本报告涉及1例37岁男性患者,其牙龈出现持续性溃疡肿胀,长期以来被误诊为牙龈瘤。诊断为低度恶性肌成纤维细胞肉瘤后,患者接受了下颌骨联合部节段性截骨术以完整切除肿瘤。术后18个月期间无复发或转移迹象。

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