Department of Otorhinolaryngology Head and Neck Surgery, Liaocheng People's Hospital, Liaocheng, China.
Shandong First Medical University (Shandong Academy of Medical Sciences), Jinan, China.
J Int Med Res. 2023 Sep;51(9):3000605231193929. doi: 10.1177/03000605231193929.
Low-grade myofibroblastic sarcoma (LGMS) is a rare malignant mesenchymal tumor derived from myofibroblasts. It is commonly identified in the head and neck, and particularly in the oral cavity, but rarely in the larynx. In this case report, we describe a patient who presented with hoarseness and underwent electronic fiber laryngoscopy, which revealed a neoplasm on the surface of his left vocal cord. The vocal cord tumor was resected under general anesthesia, and a malignant LGMS was diagnosed on postoperative pathologic examination. The results of immunohistochemical staining of the sections for vimentin (diffuse +), actin (partial +), and desmin (-) were consistent with this diagnosis. The patient recovered well after the surgery, and there was no recurrence of the neoplasm.
低度恶性肌纤维母细胞瘤(LGMS)是一种罕见的来源于肌纤维母细胞的恶性间叶性肿瘤。它通常发生在头颈部,特别是口腔,但在喉部很少见。在本病例报告中,我们描述了一位以声音嘶哑就诊的患者,行电子纤维喉镜检查发现其左侧声带表面有一肿物。在全身麻醉下切除声带上的肿瘤,术后病理检查诊断为恶性 LGMS。免疫组化染色结果显示波形蛋白(弥漫+)、肌动蛋白(部分+)、结蛋白(-),与该诊断相符。患者术后恢复良好,肿物无复发。