Bedello P, De Paoli M
Clinica Dermatologica, Università degli Studi di Torino.
G Ital Dermatol Venereol. 1990 Jun;125(6):XIX-XXI.
Eighteen male patients, mean aged of 55.7 years, affected by psoriasis were treated for an average of 19 days with fluocinolone acetonide (FA) using an occlusive traditional dressing with a 0.025% cream or with a medicated plastic porous tape (8 micrograms/cm2), according to a controlled hemipart design. The average total quantity of FA administrated for each patient was 3.431 mg on the side treated with tape and 19.827 mg on the side treated with cream. Both the treatments showed excellent efficacy (ANOVA between times p less than 0.01), better with the tape than with the occlusive conventional dressing. The patients preferred the use of the tape to the cream. The tolerability was very good. Treatment with the medicated tape was shown to be more effective than the occlusive traditional dressing, and yielded a reduction of the quantity of corticosteroid administrated to the patients.
18名患有银屑病的男性患者，平均年龄55.7岁，根据对照半侧设计，使用0.025%的乳膏进行封闭传统敷料治疗，或使用含药塑料多孔胶带（8微克/平方厘米），用氟轻松丙酮缩合物（FA）平均治疗19天。每位患者在使用胶带治疗的一侧平均给予FA总量为3.431毫克，在使用乳膏治疗的一侧为19.827毫克。两种治疗均显示出极佳的疗效（时间间方差分析p<0.01），使用胶带的效果优于封闭传统敷料。患者更喜欢使用胶带而非乳膏。耐受性非常好。含药胶带治疗比封闭传统敷料更有效，且减少了给予患者的皮质类固醇剂量。
