Colburn Jessica L, Jasinski Donald R, Rastegar Darius A
Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J Opioid Manag. 2012 May-Jun;8(3):153-60. doi: 10.5055/jom.2012.0111.
To compare rates of opioid prescribing, aberrant behaviors, and indicators of substance misuse in patients prescribed long-term opioids by resident physicians or attending physicians in a general internal medicine practice.
Medical records of 333 patients who were prescribed opioids for at least three consecutive months were reviewed. Aberrant behaviors over a 2-year period were documented, including reporting lost or stolen medications or receiving opioids from more than one provider. Indicators of substance misuse were also recorded, including positive urine drug testing for illicit substances, addiction treatment, overdose, and altering prescriptions.
An estimated 13.6 percent of the patients followed by residents had been prescribed opioids for three or more months; this was significantly higher than the rate for attendings (5.9 percent, p < 0.001). Patients followed by residents were more likely to have reported lost or stolen prescriptions or medication (25.7 percent vs 12.2 percent, p = 0.03) or to have received opioids from another provider (17.8 percent vs 7.6 percent, p = 0.008); they were also more likely to exhibit an indicator of substance misuse (24.8 percent vs 7.6 percent, p < 0.001). However, in multivariate analyses, aberrant behaviors and indicators of substance misuse were not significantly associated with having a resident physician.
Resident physicians at our institution are following a disproportionate number of patients on long-term opioids, many of whom exhibit aberrant behaviors and indicators of substance misuse. This underscores a need for better resident training and supervision to provide effective and safe care for patients with chronic pain.
比较在普通内科实践中,由住院医师或主治医师开具长期阿片类药物处方的患者中,阿片类药物的处方率、异常行为及药物滥用指标。
回顾了333例连续至少三个月开具阿片类药物处方患者的病历。记录了两年期间的异常行为,包括报告药物丢失或被盗,或从多个提供者处获取阿片类药物。还记录了药物滥用指标,包括非法物质尿液药物检测呈阳性、成瘾治疗、过量用药及更改处方。
估计由住院医师随访的患者中有13.6%被开具阿片类药物三个月或更长时间;这显著高于主治医师的比例(5.9%,p<0.001)。由住院医师随访的患者更有可能报告处方或药物丢失或被盗(25.7%对12.2%,p = 0.03),或从其他提供者处获取阿片类药物(17.8%对7.6%,p = 0.008);他们也更有可能表现出药物滥用指标(24.8%对7.6%,p<0.001)。然而,在多变量分析中,异常行为和药物滥用指标与有住院医师并无显著关联。
我们机构的住院医师随访的长期使用阿片类药物的患者数量不成比例,其中许多患者表现出异常行为和药物滥用指标。这凸显了需要更好地培训和监督住院医师,以便为慢性疼痛患者提供有效且安全的护理。