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5-(Adamantan-1-yl)-3-[(4-benzyl-piperazin-1-yl)meth-yl]-1,3,4-oxadiazole-2(3H)-thione.

作者信息

El-Emam Ali A, El-Brollosy Nasser R, Attia Mohamed I, Said-Abdelbaky Mohammed, García-Granda Santiago

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2172-3. doi: 10.1107/S1600536812027249. Epub 2012 Jun 23.

Abstract

The mol-ecule of the title compound, C(24)H(32)N(4)OS, is a functionalized 1,3,4-oxadiazole-2-thione with substituted piperazine and adamantanyl substituents attached at the 3- and 5-positions, respectively, of the oxadiazole spacer with an approximately C-shaped conformation. In the crystal, mol-ecules form dimers via C-H⋯S inter-action. The piperazine ring has a chair conformation; the substituents S, methyl-ene C and adamantane C of the essentially planar oxadiazole ring are approximately in the same plane, with distances of -0.046 (2), -0.085 (5) and 0.003 (4) Å, respectively. The dihedral angle between the planes of the phenyl and oxadiazole rings is 31.3 (3)°.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1aab/3393978/efc188568c48/e-68-o2172-fig1.jpg

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