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3-(1-金刚烷基)-1-{[4-(2-甲氧基苯基)哌嗪-1-基]甲基}-4-甲基-1H-1,2,4-三唑-5(4H)-硫酮

3-(1-Adamant-yl)-1-{[4-(2-meth-oxy-phen-yl)piperazin-1-yl]meth-yl}-4-methyl-1H-1,2,4-triazole-5(4H)-thione.

作者信息

Al-Tamimi Abdul-Malek S, Bari Ahmed, Al-Omar Mohamed A, Alrashood Khalid A, El-Emam Ali A

机构信息

Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia.

出版信息

Acta Crystallogr Sect E Struct Rep Online. 2010 Jun 23;66(Pt 7):o1756. doi: 10.1107/S1600536810022695.

Abstract

The title compound, C(25)H(35)N(5)OS, is a functionalized triazoline-3-thione with substituted piperazine and adamantyl substituents attached at the 2- and 5-positions, respectively, of a triazole spacer with an approximately C-shaped conformation of the mol-ecule. The piperazine ring adopts a chair conformation.

摘要

标题化合物C(25)H(35)N(5)OS是一种功能化的三唑啉-3-硫酮,在具有近似C形分子构象的三唑间隔基的2位和5位分别连接有取代的哌嗪和金刚烷基取代基。哌嗪环呈椅式构象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/de27/3006920/7f04423f3074/e-66-o1756-fig1.jpg

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