Wang Shuo, Shan Guangzhi, Guo Huiyuan, Liu Mingliang
Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Tiantan Xili 1#, Beijing, People's Republic of China.
Acta Crystallogr Sect E Struct Rep Online. 2012 Jul 1;68(Pt 7):o2264. doi: 10.1107/S1600536812028711. Epub 2012 Jun 30.
In the title structure, C(25)H(24)FN(3)O(5), a strong intra-molecular O-H⋯O hydrogen bond is present between the carb-oxy group at the 3-position and the carbonyl group at the 4-position. In the crystal, mol-ecules are held together by weak C-H⋯O, C-H⋯F and π-π [centroid-centroid distance 3.6080 (8) Å] inter-actions. The 1,4-dihydro-quinoline ring and cyclo-propyl group are not in the same plane, making an inter-planar angle of 57.52 (8)°.