HUANG Zhen-yun, LIU Da-bo, ZHONG Jian-wen, ZHOU Jing, XU Jia-jian, ZHOU Yu-ping, QIU Shu-yao, LIU Shao-feng
Department of Otorhinolaryngology, Guangzhou Women and Children's Medical Center, Guangzhou 510120, China.
Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Apr;47(4):274-9.
To explore which index is more suitable to show the degree of sleep fragment in children with sleep-disordered breathing (SDB).
Between October 2009 and August 2011, Forty-five children (4 - 8 years) who were diagnosed as obstructive sleep apnea hypopnea syndrome (OSAHS) were enrolled in OSAHS group[obstructive apnea index (OAI) > 1 times/h or apnea hypopnea index (AHI) > 5 times/h, lowest oxygen saturation (LSaO2) < 0.92] and 54 children were enrolled in SDB group (1 ≤ AHI ≤ 5 times/h and OAI ≤ 1 times/h), 18 children with chorditis nodules made up control group (AHI < 1 times/h and LSaO2 ≥ 0.92, without SDB-related history). The difference of respiratory arousal index (RAI), spontaneous arousal index (SAI), total arousal index (ARtotI) and sleep pressure score (SPS) were compared among three groups. The correlation between RAI, SAI, ARtotI, SPS and AHI were also analyzed. Furthermore, RAI, SAI, ARtotI and SPS were compared before and after operation in 14 OSAHS children with detailed pre- and after polysomnography data.
The difference of SAI and ARtotI between SDB group and OSAHS group and ARtotI between OSAHS group and control group were not significant (P > 0.017), except this, the difference of other index between any two groups or SAI and ARtotI between otherwise two groups were significant (P < 0.017). RAI and SPS was correlated with AHI (coefficient correlation: 0.751, 0.829, P was 0.000). RAI and SPS decreased after operation and the difference was significant (Z were -3.045 and -2.982, P were 0.002 and 0.003). The difference of sleep structure was not significant.
RAI and SPS were more suitable to show the degree of sleep fragment than other arousal index.
探讨哪种指标更适合用于显示睡眠呼吸障碍（SDB）儿童的睡眠片段化程度。
2009年10月至2011年8月，45例4至8岁被诊断为阻塞性睡眠呼吸暂停低通气综合征（OSAHS）的儿童纳入OSAHS组[阻塞性呼吸暂停指数（OAI）>1次/小时或呼吸暂停低通气指数（AHI）>5次/小时，最低血氧饱和度（LSaO2）<0.92]，54例儿童纳入SDB组（1≤AHI≤5次/小时且OAI≤1次/小时），18例患有声带小结的儿童组成对照组（AHI<1次/小时且LSaO2≥0.92，无SDB相关病史）。比较三组间呼吸唤醒指数（RAI）、自发唤醒指数（SAI）、总唤醒指数（ARtotI）和睡眠压力评分（SPS）的差异。还分析了RAI、SAI、ARtotI、SPS与AHI之间的相关性。此外，对14例有详细术前和术后多导睡眠图数据的OSAHS儿童，比较其手术前后的RAI、SAI、ARtotI和SPS。
SDB组与OSAHS组之间SAI和ARtotI的差异以及OSAHS组与对照组之间ARtotI的差异无统计学意义（P>0.017），除此之外，任意两组之间其他指标的差异或另外两组之间SAI和ARtotI的差异均有统计学意义（P<0.017）。RAI和SPS与AHI相关（相关系数分别为：0.751、0.829，P均为0.000）。手术后RAI和SPS降低，差异有统计学意义（Z分别为-3.045和-2.982，P分别为0.002和0.003）。睡眠结构差异无统计学意义。
与其他唤醒指数相比，RAI和SPS更适合用于显示睡眠片段化程度。
