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[长段髂股动脉闭塞性疾病的治疗:两例解剖外旁路手术]

[Treatment of long-segment iliofemoral occlusive disease: two extra-anatomic bypass surgeries].

作者信息

Ma Jie, Ma Tao, Wang Ren, Zhao Xu, Li Yue-meng

机构信息

Vascular Surgery Department, Dalian Municipal Central Hospital, Dalian 116033, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2012 Apr;50(4):306-9.

Abstract

OBJECTIVE

To report and evaluate the clinical results of surgical treatment for long-segment iliofemoral arteriosclerosis obliterans, including external iliac-popliteal (EIP) and femoral-deep femoral (FDF) crossover bypass surgeries.

METHODS

From July 1995 to December 2009, 85 patients (61 male, 24 female, aged from 64 to 91 years, mean age 75 years) with comprehensive unilateral iliac-superficial femoral arteriosclerosis obliterans were involved in this research. According to Fontaine classification, the 85 patients could be graded as 62 class IIb-III patients (72.9%), and 23 class IV patients (27.1%). In CT angiography or DSA examinations, the 85 patients were grouped into EIP (n = 49) and FDF (n = 36) surgical groups on the basis of visualizations in the affected deep femoral, supra-knee/infra-knee popliteal arteries. The healing time of ulcers and toe amputation wound, ankle-brachial index, and blood flow velocity in the affected limb together with accumulative patency rates in 1, 3 and 5 years and limb salvage rates in 3 and 5 years were analyzed.

RESULTS

None of the 85 patients died or had extremity amputated in perioperatively. Seventy-four patients (87.1%) had been followed up from 2 to 13 years (mean 5.7 years). Postoperative ankle-brachial index of FDF and EIP groups was 0.55 ± 0.11, and 0.94 ± 0.13 (t = -21.88, P = 0.000). Postoperative velocity of popliteal artery blood flow in FDF and EIP groups was (32 ± 9) cm/s, and (48 ± 4) cm/s (t = 16.76, P = 0.000); velocity of anterior or posterior tibial artery was (22 ± 7) cm/s, and (42 ± 4) cm/s (t = 10.50, P = 0.000). The primary and secondary patency rates of FDF and EIP groups were 87.8% and 88.3%, 80.7% and 81.2%, 68.4% and 57.4% at 1, 3 and 5 years, respectively. Limb salvage rates of FDF and EIP groups were 87.6% and 88.6%, 76.7% and 71.3%, at 3 and 5 years, respectively. There were no statistically significant differences in 1, 3, and 5 years' cumulative secondary patency rate and limb salvage rate between FDF and EIP groups.

CONCLUSIONS

As extra-anatomic bypass surgeries, FDF and EIP are both determined to be alternative procedures for unilateral common iliac-superficial femoral artery occlusive disease, especially suitable for high-risk patients. EIP group patients have better clinical outcomes than those in FDF group.

摘要

目的

报告并评估长段髂股动脉硬化闭塞症手术治疗的临床结果,包括髂外-腘动脉(EIP)和股-股深动脉(FDF)交叉搭桥手术。

方法

1995年7月至2009年12月,85例(男61例,女24例,年龄64至91岁,平均年龄75岁)单侧髂总-股浅动脉硬化闭塞症患者纳入本研究。根据Fontaine分级,85例患者中62例为IIb-III级患者(72.9%),23例为IV级患者(27.1%)。在CT血管造影或DSA检查中,85例患者根据患侧股深动脉、膝上/膝下腘动脉的显影情况分为EIP手术组(n = 49)和FDF手术组(n = 36)。分析溃疡和趾截肢伤口的愈合时间、踝肱指数、患侧肢体血流速度以及1年、3年和5年的累积通畅率和3年、5年的肢体挽救率。

结果

85例患者围手术期均无死亡或肢体截肢情况。74例患者(87.1%)获得2至13年(平均5.7年)的随访。FDF组和EIP组术后踝肱指数分别为0.55±0.11和0.94±0.13(t = -21.88,P = 0.000)。FDF组和EIP组术后腘动脉血流速度分别为(32±9)cm/s和(48±4)cm/s(t = 16.76,P = 0.000);胫前或胫后动脉血流速度分别为(22±7)cm/s和(42±4)cm/s(t = 10.50,P = 0.000)。FDF组和EIP组1年、3年和5年的初次和二次通畅率分别为87.8%和88.3%、80.7%和81.2%、68.4%和57.4%。FDF组和EIP组3年和5年的肢体挽救率分别为87.6%和88.6%、76.7%和71.3%。FDF组和EIP组1年、3年和5年的累积二次通畅率和肢体挽救率差异无统计学意义。

结论

作为解剖外搭桥手术,FDF和EIP均被确定为单侧髂总-股浅动脉闭塞性疾病的替代手术方法,尤其适用于高危患者。EIP组患者的临床结局优于FDF组。

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