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鼻腔黏膜温度作为变应性鼻炎患儿疾病标志物的研究

Nasal mucosa temperature as a marker of disease in children with allergic rhinitis.

机构信息

Department of Paediatrics, University of Verona, Verona, Italy.

出版信息

Am J Rhinol Allergy. 2012 Jul-Aug;26(4):e115-8. doi: 10.2500/ajra.2012.26.3803.

Abstract

BACKGROUND

Allergic rhinitis (AR) is a symptomatic disorder of the nose induced after allergen exposure by an IgE-mediated inflammation of the nasal mucosa. This study was designed to investigate the role of nasal mucosa temperature in AR.

METHODS

We investigated the relationship between eosinophilic infiltration, nasal obstruction, and nasal mucosa temperature in 35 children with rhinitis aged 6-12 years.

RESULTS

A significant relationship was shown between nasal temperature values and eosinophil infiltration at nasal cytology (p < 0.01). Nasal temperature was also significantly associated with nasal obstruction, assessed in terms of nasal volume (Vol [2-5 cm]; p < 0.05) and minimum cross-sectional area (p < 0.01). No significant correlation emerged between the degree of nasal obstruction and presence of eosinophils at nasal cytology (p > 0.05).

CONCLUSION

These results suggest a relationship between nasal temperature and nasal mucosa inflammation and obstruction.

摘要

背景

变应性鼻炎(AR)是一种鼻症状性疾病,由过敏原暴露后 IgE 介导的鼻黏膜炎症引起。本研究旨在探讨鼻黏膜温度在 AR 中的作用。

方法

我们调查了 35 名 6-12 岁患有鼻炎的儿童的嗜酸性粒细胞浸润、鼻塞和鼻黏膜温度之间的关系。

结果

鼻温度值与鼻细胞学检查中的嗜酸性粒细胞浸润呈显著相关(p<0.01)。鼻温度与鼻腔容积(Vol [2-5 cm];p<0.05)和最小横截面积(p<0.01)评估的鼻塞也显著相关。鼻细胞学检查中鼻塞程度与嗜酸性粒细胞之间无显著相关性(p>0.05)。

结论

这些结果表明,鼻温度与鼻黏膜炎症和阻塞之间存在关系。

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