Moayedi Yasbanoo, Venos Erik Steven, Ghaffar Hasan, Gough Kevin A, Hicks Lisa K
Department of Medicine, University of Toronto, Toronto, Ontario, Canada.
BMJ Case Rep. 2012 Jul 13;2012:bcr2012006452. doi: 10.1136/bcr-2012-006452.
Plasmablastic lymphoma (PBL) is a variant of lymphoma originally described in the oral cavity of patients with advanced HIV. Our patient developed PBL despite well-controlled HIV and a CD4 count greater than 800 cells/µl. A drug interaction with an inhaled corticosteroid and ritonavir likely contributed to the development of this malignancy through increased immune suppression.
浆母细胞淋巴瘤(PBL)是一种淋巴瘤变体,最初在晚期HIV患者的口腔中被描述。尽管我们的患者HIV病情得到良好控制且CD4细胞计数大于800个/微升,但仍发生了PBL。吸入性糖皮质激素与利托那韦之间的药物相互作用可能通过增强免疫抑制作用促成了这种恶性肿瘤的发生。