Wix-Ramos Richard Joseph, Capote Eduardo, Mendoza Milet, Garcia Margreth, Ezequiel Uribe
Department of Physiological Sciences, Faculty of Health Sciences, University of Carabobo, Carabobo, Venezuelaa.
Pol J Radiol. 2011 Apr;76(2):49-51.
A male patient, 44 years old, with schizophrenia which started at the age of 18. At his last follow-up visit, laboratory tests and brain magnetic resonance imaging (MRI) were performed, revealing the presence of a sellar arachnoidocele. To our knowledge, there is only one similar case report of a set of male monozygotic triplets with schizophrenia and empty sella syndrome. High-resolution chromosome analysis found an extra band at chromosome 15p in all the triplets and their father. We performed a similar evaluation in our patient and his family to compare the results and identify new information on neuroanatomical abnormalities, hormonal alterations or genetic origins of schizophrenia.
一名44岁男性患者，18岁起患精神分裂症。在他最后一次随访时，进行了实验室检查和脑磁共振成像（MRI），结果显示存在鞍区蛛网膜囊肿。据我们所知，仅有一例类似病例报告，是一组患有精神分裂症和空蝶鞍综合征的男性单卵三胞胎。高分辨率染色体分析发现，所有三胞胎及其父亲的15号染色体短臂均有一条额外的带。我们对该患者及其家人进行了类似评估，以比较结果并确定有关精神分裂症的神经解剖学异常、激素改变或遗传起源的新信息。
