Val-Bernal José Fernando, González-Vela María Carmen, De Grado Mauricio, Garijo María Francisca
Anatomical Pathology Department, Marqués de Valdecilla, University Hospital, Medical Faculty, University of Cantabria and IFIMAV, Santander, Spain.
J Cutan Pathol. 2012 Aug;39(8):798-802. doi: 10.1111/j.1600-0560.2012.01940.x. Epub 2012 Jul 16.
Accessory breast tissue is a subcutaneous remnant persisting after normal embryological development of the breast. It occurs most frequently in the axilla. Fibroadenomas in axillary breast tissue are rare. We report the case of a 29-year-old female patient who presented a fibroadenoma arising in the accessory breast tissue of the right axillary fossa. The neoplasm showed foci of sclerotic fibroma-like stroma. The patient had no signs of Cowden's syndrome. To the best of our knowledge, a lesion of this kind has not been previously reported. This stromal change suggests an uncommon involutional phase of the fibroadenoma with production of sclerotic and hypocellular collagen. The lesion should be differentiated from extraneural perineuroma, from the changes in fibroadenomas in Cowden's syndrome, from sclerosing lobular hyperplasia (fibroadenomatoid mastopathy) and from pseudoangiomatous stromal hyperplasia.
副乳腺组织是乳房正常胚胎发育后残留的皮下组织。它最常发生于腋窝。腋窝乳腺组织中的纤维腺瘤罕见。我们报告一例29岁女性患者,其右腋窝副乳腺组织出现纤维腺瘤。该肿瘤显示出硬化性纤维瘤样间质灶。患者无考登综合征体征。据我们所知,此前尚未报道过此类病变。这种间质变化提示纤维腺瘤处于不常见的 involutional 期,伴有硬化性和细胞减少性胶原的产生。该病变应与神经外神经鞘瘤、考登综合征中纤维腺瘤的变化、硬化性小叶增生(纤维腺瘤样乳腺病)以及假血管瘤样间质增生相鉴别。