Division of Ophthalmology, Nemours Children's Clinic, Wilmington, Delaware 19803, USA.
Curr Opin Ophthalmol. 2012 Sep;23(5):384-7. doi: 10.1097/ICU.0b013e3283566b4b.
Cortical visual impairment (CVI) is a major cause of visual loss in children worldwide. The definition of this condition is constantly evolving with respect to definition, identifying those at risk and technology for diagnosis. These advances can be used for early diagnosis, design of accommodations and services, as well as future therapies and prevention strategies.
Clinical questionnaires are being developed and tested for reliability in an attempt to identify those at risk for CVI. The definition is constantly being modified and now includes deficits in vision-guided motor planning and higher level executive functions. Neuroimaging techniques, such as MRI, functional MRI, and diffusion tensor imaging; electrophysiologic testing, such as sweep visual-evoked potentials; and perceptual testing, allow for further refinements in correlating structural defects and deficits in function.
Recent developments will allow identification of those children at risk for CVI and earlier interventions for specific deficits. A child's performance is built on previously mastered skills, making timely prediction of deficits and intervention essential.
皮质视觉障碍(CVI)是全球儿童视力丧失的主要原因。该病症的定义不断演变,涉及定义、确定风险人群以及诊断技术。这些进展可用于早期诊断、适应和服务设计,以及未来的治疗和预防策略。
正在开发和测试临床问卷,以试图识别那些有患 CVI 风险的人群。该定义不断被修改,现在包括视力引导运动规划和高级执行功能的缺陷。神经影像学技术,如 MRI、功能 MRI 和弥散张量成像;电生理测试,如扫视视觉诱发电位;以及知觉测试,使得在关联结构缺陷和功能缺陷方面可以进一步细化。
最近的发展将允许识别那些有患 CVI 风险的儿童,并对特定缺陷进行早期干预。儿童的表现是建立在以前掌握的技能基础上的,因此及时预测缺陷和进行干预至关重要。