Mackenzie Shawn D, Blois Shauna, Hayes Galina, Vince Andrew R
Health Sciences Center, Ontario Veterinary College, University of Guelph, Guelph, ON Canada.
J Vet Emerg Crit Care (San Antonio). 2012 Aug;22(4):494-7. doi: 10.1111/j.1476-4431.2012.00781.x. Epub 2012 Jul 16.
To describe the clinical features, diagnostic work-up, treatment, and outcome of a dog with oral thermal injury secondary to chewing on a salbutamol metered-dose inhaler (MDI).
A Boxer dog was presented after chewing on a salbutamol MDI. The dog was anxious, tachycardic and had moderate hypokalemia. The dog was treated with potassium supplementation and discharged after 24-hour hospitalization. Five hours after the discharge, the dog represented for dysphagia, anorexia, cervical pain, and a left-sided head tilt. Oral examination revealed edematous and erythematous swelling of the soft palate causing airway compromise; histopathology demonstrated vascular necrosis and infarction. The dog was treated with supportive care including the placement of a tracheostomy tube. The dog recovered fully and was discharged 8 days after initial presentation.
Salbutamol toxicity has been documented previously in dogs but oral thermal injury associated with a salbutamol MDI has not been reported in dogs. Although a rare complication, dogs who have been exposed to MDIs should have a thorough oral exam and be monitored closely for signs of respiratory compromise.
描述一只因咀嚼沙丁胺醇定量吸入器(MDI)而导致口腔热损伤的犬的临床特征、诊断检查、治疗及预后情况。
一只拳师犬在咀嚼沙丁胺醇MDI后就诊。该犬表现焦虑、心动过速且有中度低钾血症。给予补钾治疗,住院24小时后出院。出院5小时后,该犬因吞咽困难、厌食、颈部疼痛和左侧头部倾斜再次就诊。口腔检查发现软腭水肿、红斑肿胀,导致气道受压;组织病理学显示血管坏死和梗死。对该犬进行了包括气管切开管置入在内的支持治疗。该犬完全康复,初次就诊8天后出院。
此前已有犬类沙丁胺醇中毒的记录,但犬类因沙丁胺醇MDI导致口腔热损伤的情况尚未见报道。尽管是罕见并发症,但接触过MDI的犬应进行全面口腔检查,并密切监测呼吸受压迹象。