Bretz Stacey Lowery, Linenberger Kimberly J
Department of Chemistry & Biochemistry, Miami University, Oxford, Ohio 45056, USA.
Biochem Mol Biol Educ. 2012 Jul;40(4):229-33. doi: 10.1002/bmb.20622. Epub 2012 Jun 18.
Enzyme function is central to student understanding of multiple topics within the biochemistry curriculum. In particular, students must understand how enzymes and substrates interact with one another. This manuscript describes the development of a 15-item Enzyme-Substrate Interactions Concept Inventory (ESICI) that measures student understanding of enzyme-substrate interactions. The validity and reliability of ESICI data were established through multiple methods. Results from the administration of the ESICI to biochemistry students across the United States (N=707) are discussed in terms of instrument quality. The manuscript concludes with suggestions for how to use the ESICI for both teaching and biochemistry education research.
酶的功能对于学生理解生物化学课程中的多个主题至关重要。特别是，学生必须理解酶和底物是如何相互作用的。本文描述了一个包含15个条目的酶-底物相互作用概念量表（ESICI）的开发，该量表用于测量学生对酶-底物相互作用的理解。ESICI数据的有效性和可靠性通过多种方法得以确立。根据工具质量，讨论了在美国各地向生物化学专业学生（N = 707）施测ESICI的结果。本文最后提出了关于如何将ESICI用于教学和生物化学教育研究的建议。
