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甲状腺切除术的结果:全国视角。

Thyroidectomy outcomes: a national perspective.

机构信息

George Washington University School of Medicine and Health Sciences, Washington, DC 20010, USA.

出版信息

Otolaryngol Head Neck Surg. 2012 Dec;147(6):1027-34. doi: 10.1177/0194599812454401. Epub 2012 Jul 16.

DOI:10.1177/0194599812454401
PMID:22807486
Abstract

OBJECTIVES

Describe trends and outcomes of patients undergoing thyroidectomy.

STUDY DESIGN AND SETTING

Retrospective search of national inpatient database.

SUBJECTS AND METHODS

The Nationwide Inpatient Sample 2009 was searched using International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes for thyroidectomy. Data extraction included patient demographics, hospital characteristics, and associated diagnoses. Subgroup analysis was performed on mortalities; bivariate and multivariate analysis was used to examine predictors of complications.

RESULTS

In the United States, 59,478 patients were admitted and underwent thyroidectomy in 2009. Their mean (SD) age was 53.0 (16.4) years. Mean (SD) length of stay was 3.0 (6.9) days, and mean (SD) total charges was $39,236 ($73,679). Total thyroidectomy was performed in 53.6% of patients; 33.2% underwent unilateral lobectomy. Most common thyroid disorders included nontoxic nodular goiter (36.0%) and malignant neoplasm (30.3%). There were 363 (0.61%) mortalities, with a mean (SD) age of 65.5 (15.2) years, length of stay of 13.9 (15.2) days, and total charges of $218,855 ($191,977). Of all patients, 6.18% had hypocalcemia and 0.77% had hypoparathyroidism; the incidence of vocal cord paresis was 0.85% unilaterally and 0.34% bilaterally. Multivariate analysis revealed predictors of complications following thyroid surgery were female sex (P = .0001), total thyroidectomy procedure (P < .0001), hospital location and teaching status (P = .0060), hospital bed size (P = .0054), type of thyroid disorder, and underlying patient comorbidities.

CONCLUSION

Reporting of normative data for thyroidectomy facilitates comparison. Hospitalizations for patients undergoing thyroidectomy require significant resource utilization. Predictors of complications include female sex, type of thyroid disorder and procedure, hospital location and teaching status, hospital bed size, and patient comorbidities.

摘要

目的

描述甲状腺切除术患者的趋势和结果。

研究设计和设置

全国住院患者数据库的回顾性检索。

受试者和方法

使用国际疾病分类,第九修订版,临床修正(ICD-9-CM)代码搜索 2009 年全国住院患者样本,进行甲状腺切除术。数据提取包括患者人口统计学、医院特征和相关诊断。对死亡率进行亚组分析;使用双变量和多变量分析来检查并发症的预测因素。

结果

在美国,2009 年有 59478 名患者入院并接受甲状腺切除术。他们的平均(SD)年龄为 53.0(16.4)岁。平均(SD)住院时间为 3.0(6.9)天,平均(SD)总费用为 39236 美元(73679 美元)。53.6%的患者行甲状腺全切除术;33.2%行单侧叶切除术。最常见的甲状腺疾病包括非毒性结节性甲状腺肿(36.0%)和恶性肿瘤(30.3%)。有 363 例(0.61%)死亡,平均(SD)年龄为 65.5(15.2)岁,住院时间为 13.9(15.2)天,总费用为 218855 美元(191977 美元)。所有患者中,6.18%有低钙血症,0.77%有甲状旁腺功能减退症;声带麻痹的发生率为单侧 0.85%,双侧 0.34%。多变量分析显示甲状腺手术后并发症的预测因素为女性(P=0.0001)、甲状腺全切除术(P<0.0001)、医院位置和教学地位(P=0.0060)、医院床位数(P=0.0054)、甲状腺疾病类型和患者合并症。

结论

报告甲状腺切除术的规范数据有助于比较。接受甲状腺切除术的患者住院需要大量资源。并发症的预测因素包括女性、甲状腺疾病类型和手术类型、医院位置和教学地位、医院床位数以及患者合并症。

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