Deasy A M, Walker B, Layton A M, Lacey C J N
Centre for Immunology and Infection, Hull York Medical School, University of York, York, UK.
Int J STD AIDS. 2012 Jun;23(6):e11-3. doi: 10.1258/ijsa.2009.009314.
Sweet's syndrome is a rare skin condition associated with both drug treatment and a number of different disease processes including haematological malignancies, inflammatory conditions and HIV infection. In this case report, we present a patient with HIV, haemophilia and hepatitis C who presented to our team with significant thrombocytopaenia and Sweet's syndrome. We discuss the difficulties with diagnosis and management in the context of multiple co-morbidities and suggest that both hepatitis C and HIV may have been aetiologically involved by suppressing platelet production and also causing bone marrow-driven neutrophilic disease.
斯威特综合征是一种罕见的皮肤疾病，与药物治疗以及多种不同的疾病过程相关，包括血液系统恶性肿瘤、炎症性疾病和HIV感染。在本病例报告中，我们介绍了一名患有HIV、血友病和丙型肝炎的患者，该患者因严重血小板减少症和斯威特综合征前来我们团队就诊。我们讨论了在多种合并症背景下诊断和管理的困难，并提出丙型肝炎和HIV可能在病因上都参与其中，既抑制了血小板生成，又导致了骨髓驱动的嗜中性粒细胞疾病。
