Institute for Maternal and Child Health, IRCCS Burlo Garofolo, Trieste, Italy.
Int J Gen Med. 2012;5:511-6. doi: 10.2147/IJGM.S31977. Epub 2012 Jun 15.
The Friuli Venezia Giulia (FVG), a region of North Eastern Italy, has passed legislation (Decree No 2324/2010) to regulate the banking of umbilical cord blood samples for personal, autologous, or family-directed use, and to implement the Agreement of the State-Regions Permanent Conference (Decree No 62/CSR/2010). This paper aims to identify the formalities and the reasons why families collect and bank their cord blood in foreign banks for both personal and private use.
To this end, at the Institute for Maternal and Child Health of Trieste (the regional capital city of the FVG), Italy, which assists about 1800 pregnant women a year, 129 questionnaires, drafted from January 2010 to December 2011 and concerning the granting of authorization to export samples, were examined.
The collected data showed that 75% of involved families had resorted to anonymous public collection, which is available to anyone with therapeutic needs, and provided compatibility and hematologic protocols recognized by the scientific and international community (main indications: leukemia, hemoglobinopaties, and inherited hematologic and immunologic disorders). Conversely, 25.0% requested private storage at a foreign bank for personal or family-dedicated use. The principal motivation by disease was for treatment for diabetes (22.4%) and celiac disease (19.7%) (a multiorgan disease for which the FVG region has provided safeguards by approving a specific law granting support to families; Decree No 561/2007). For these two types of disease we found that information was received from the internet and not from general medical physicians, with a significant difference found using the χ(2) test (P < 0.01).
The indication of treating these diseases with cord blood stem cell transplantation appears to be well grounded and encouraging, and has recently been corroborated by the international literature; however, the economic and social motivations promoting cord blood storage, for a fee, in the event of diseases that are still under study, require accurate information through general medical physicians on the actual possibilities of treatment.
意大利东北部弗留利-威尼斯朱利亚（FVG）地区通过立法（第 2324/2010 号法令）规范脐带血样本的银行存储，用于个人、自体或家庭定向使用，并实施国家-地区常设会议协议（第 62/CSR/2010 号法令）。本文旨在确定家庭为个人和私人用途在外国银行收集和存储脐带血的手续和原因。
为此，在意大利的的里雅斯特（FVG 的首府）的母婴健康研究所（每年为约 1800 名孕妇提供服务），检查了 2010 年 1 月至 2011 年 12 月期间起草的 129 份关于授权出口样本的问卷。
收集的数据显示，75%的相关家庭求助于匿名公共采集，供有治疗需求的任何人使用，并提供科学和国际社会认可的相容性和血液学方案（主要适应症：白血病、血红蛋白病、遗传性血液和免疫疾病）。相反，25.0%的家庭要求在外国银行进行私人存储，用于个人或家庭专用。主要的疾病动机是治疗糖尿病（22.4%）和乳糜泻（19.7%）（这是一种多器官疾病，FVG 地区通过批准一项具体法律为家庭提供支持来对此提供保障；第 561/2007 号法令）。对于这两种疾病，我们发现信息是从互联网上获得的，而不是从普通内科医生那里获得的，χ(2)检验有显著差异（P <0.01）。
用脐带血干细胞移植治疗这些疾病的适应症似乎是合理和令人鼓舞的，最近也得到了国际文献的证实；然而，为了在仍在研究中的疾病而付费存储脐带血的经济和社会动机，需要通过普通内科医生提供关于实际治疗可能性的准确信息。
