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齐拉西酮治疗妄想性寄生虫病。

Ziprasidone in the treatment of delusional parasitosis.

作者信息

Contreras-Ferrer P, de Paz N Merino, Cejas-Mendez M R, Rodríguez-Martín M, Souto R, Bustínduy M García

机构信息

Department of Dermatology, Hospital Universitario de Canarias, La Laguna, Spain.

出版信息

Case Rep Dermatol. 2012 May;4(2):150-3. doi: 10.1159/000341112. Epub 2012 Jul 11.

DOI:10.1159/000341112
PMID:22807899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3398084/
Abstract

Delusional parasitosis is characterized by a patient's fixed false belief of being infested with parasites or small creatures. The first-line treatment options are typical antipsychotics such as pimozide. However, the accompanying extrapyramidal side effects might limit their use. We report on a patient with a good response to pimozide combined with ziprasidone. Ziprasidone is an atypical antipsychotic drug with a lower risk of extrapyramidal symptoms; thus, it might be considered a good first or second treatment option for delusional parasitosis.

摘要

妄想性寄生虫病的特征是患者坚信自己感染了寄生虫或小生物,但这种信念是错误的。一线治疗选择是使用典型的抗精神病药物,如匹莫齐特。然而,随之而来的锥体外系副作用可能会限制其使用。我们报告了一名对匹莫齐特联合齐拉西酮治疗反应良好的患者。齐拉西酮是一种非典型抗精神病药物,锥体外系症状风险较低;因此,它可能被认为是妄想性寄生虫病的一种良好的一线或二线治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1c/3398084/08e046433b20/cde-0004-0150-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1c/3398084/f56d77b2c655/cde-0004-0150-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1c/3398084/08e046433b20/cde-0004-0150-g02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1c/3398084/f56d77b2c655/cde-0004-0150-g01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5f1c/3398084/08e046433b20/cde-0004-0150-g02.jpg

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本文引用的文献

1
The current management of delusional parasitosis and dermatitis artefacta.妄想性寄生虫病和人工皮炎的当前管理
Skin Therapy Lett. 2010 Oct;15(9):1-3.
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Delusional infestation.妄想性寄生虫感染。
Clin Microbiol Rev. 2009 Oct;22(4):690-732. doi: 10.1128/CMR.00018-09.
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Delusional parasitosis: lessons learnt.妄想性寄生虫病:经验教训
妄想性寄生虫病一例成功使用齐拉西酮单药治疗:一年随访
Case Rep Psychiatry. 2013;2013:913248. doi: 10.1155/2013/913248. Epub 2013 May 16.
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Striatal lesions in delusional parasitosis revealed by magnetic resonance imaging.磁共振成像显示的妄想性寄生虫病中的纹状体病变
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Delusional parasitosis: case series of 8 patients and review of the literature.妄想性寄生虫病:8例病例系列及文献综述
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[Delusional parasitic infestation and folie à deux: case report].[妄想性寄生虫感染与感应性精神病:病例报告]
Arq Neuropsiquiatr. 2003 Sep;61(3B):872-5. doi: 10.1590/s0004-282x2003000500033. Epub 2003 Oct 28.
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Delusional parasitosis mimicking cutaneous infestation in elderly patients.老年患者中酷似皮肤寄生虫感染的妄想性寄生虫病。
Med J Aust. 2003 Aug 18;179(4):209-10. doi: 10.5694/j.1326-5377.2003.tb05503.x.
9
[A case of delusional parasitosis in severe heart failure. Olanzapine within the framework of a multimodal therapy].[一例严重心力衰竭合并妄想性寄生虫病。奥氮平在多模式治疗中的应用]
Nervenarzt. 2003 Jul;74(7):591-5. doi: 10.1007/s00115-003-1493-6. Epub 2003 Jun 14.
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Risperidone and the treatment of delusions of parasitosis in an elderly patient.利培酮与老年寄生虫妄想症的治疗
Psychosomatics. 1995 Nov-Dec;36(6):578-80. doi: 10.1016/S0033-3182(95)71615-2.