原发性睾丸非霍奇金淋巴瘤合并噬血细胞综合征：病例报告及文献复习
Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature.
作者信息
Ren Weigang, Zhong Zhaohui, Zhao Xiaokun, Yang Junjie, Zhang Lei, Xu Ran, Li Songchao, Zhu Xuan, Lu Chen, Chin Joseph L
机构信息
Department of Urology, The Second Xiangya Hospital, Central South University, Changsha, Hunan 410011.
出版信息
Oncol Lett. 2012 Jul;4(1):59-62. doi: 10.3892/ol.2012.701. Epub 2012 Apr 30.
Abstract
Primary testicular non-Hodgkin's lymphoma (TNHL) was first described as a clinical entity in 1866. It is a rare disease which accounts for 1% of all non-Hodgkin's lymphoma, 2% of all extranodal lymphomas and 5% of all testicular neoplasms. Hemophagocytic syndrome (HPS) is a rare but distinct condition caused by inappropriate and dysregulated activation of the immune system. We report a 47-year-old man with primary TNHL who developed HPS four months after occurrence of scrotal swelling. To the best of our knowledge, primary TNHL associated with HPS has not previously been reported.
摘要
原发性睾丸非霍奇金淋巴瘤（TNHL）于1866年首次被描述为一种临床实体。它是一种罕见疾病，占所有非霍奇金淋巴瘤的1%、所有结外淋巴瘤的2%以及所有睾丸肿瘤的5%。噬血细胞综合征（HPS）是一种由免疫系统不适当和失调激活引起的罕见但独特的病症。我们报告一名47岁患有原发性TNHL的男性，其在阴囊肿胀出现四个月后发生了HPS。据我们所知，此前尚未报道过与HPS相关的原发性TNHL。
相似文献
1
Primary testicular non-Hodgkin's lymphoma associated with hemophagocytic syndrome: Case report and review of the literature.原发性睾丸非霍奇金淋巴瘤合并噬血细胞综合征：病例报告及文献复习
Oncol Lett. 2012 Jul;4(1):59-62. doi: 10.3892/ol.2012.701. Epub 2012 Apr 30.
2
Concomitant Presence of Spermatic Cord and Testicular Non-Hodgkin's Lymphoma With Recurrence: A Case Report on a Rare Entity.精索和睾丸非霍奇金淋巴瘤伴复发的同时存在：一例罕见病例报告
Cureus. 2022 Oct 11;14(10):e30182. doi: 10.7759/cureus.30182. eCollection 2022 Oct.
3
Common variable immune deficiency associated Hodgkin's lymphoma complicated with EBV-linked hemophagocytic lymphohistiocytosis: a case report.普通可变免疫缺陷相关霍奇金淋巴瘤合并EB病毒相关噬血细胞性淋巴组织细胞增生症：一例报告
Int J Clin Exp Med. 2015 Aug 15;8(8):14203-6. eCollection 2015.
4
Gallbladder non-Hodgkin's lymphoma: Case report.胆囊非霍奇金淋巴瘤：病例报告。
Int J Surg Case Rep. 2019;61:218-221. doi: 10.1016/j.ijscr.2019.07.064. Epub 2019 Jul 25.
5
Primary testicular lymphoma with solitary cutaneous nodule as the initial presentation.以孤立性皮肤结节为首发表现的原发性睾丸淋巴瘤。
Can Urol Assoc J. 2015 Sep-Oct;9(9-10):E744-7. doi: 10.5489/cuaj.3065. Epub 2015 Oct 13.
6
Testicular lymphoma: Atypical presentation of acute scrotal swelling.睾丸淋巴瘤：急性阴囊肿胀的非典型表现。
Int J Surg Case Rep. 2023 Dec;113:109027. doi: 10.1016/j.ijscr.2023.109027. Epub 2023 Nov 16.
7
Classical Hodgkin's lymphoma presenting as a testicular mass: report of a case.以睾丸肿块为表现的经典型霍奇金淋巴瘤：一例报告
Int J Surg Pathol. 2007 Apr;15(2):207-12. doi: 10.1177/1066896906299071.
8
Anaplastic T-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Case Report.
Turk J Haematol. 2003 Jun 5;20(2):101-6.
9
[Staging of non-Hodgkin's lymphoma--recommendations of the Czech Lymphoma Study Group].[非霍奇金淋巴瘤的分期——捷克淋巴瘤研究组的建议]
Klin Onkol. 2010;23(3):146-54.
10
Non-Hodgkins lymphoma of maxilla: A rare entity.上颌骨非霍奇金淋巴瘤：一种罕见的疾病。
Natl J Maxillofac Surg. 2011 Jul;2(2):210-3. doi: 10.4103/0975-5950.94485.
引用本文的文献
1
Hemophagocytic Syndrome as an Initial Presentation of Systemic Lupus Erythematosus: A Case Report.噬血细胞综合征作为系统性红斑狼疮的首发表现：一例报告
Cureus. 2019 Jul 29;11(7):e5261. doi: 10.7759/cureus.5261.
2
Case report of rare chronic myelogenous leukemia related multibacterial splenic abscess presenting with scrotal swelling.罕见的慢性粒细胞白血病相关多细菌脾脓肿伴阴囊肿胀的病例报告。
Int J Surg Case Rep. 2014;5(12):951-3. doi: 10.1016/j.ijscr.2014.10.069. Epub 2014 Oct 23.
本文引用的文献
1
Histopathologic and molecular aspects of CD56+ natural killer/ T-cell lymphoma of the testis.睾丸CD56+自然杀伤/T细胞淋巴瘤的组织病理学和分子学特征
Int J Surg Pathol. 2008 Jul;16(3):291-300. doi: 10.1177/1066896907309687.
2
Infections associated with haemophagocytic syndrome.与噬血细胞综合征相关的感染
Lancet Infect Dis. 2007 Dec;7(12):814-22. doi: 10.1016/S1473-3099(07)70290-6.
3
Hemophagocytic syndromes.噬血细胞综合征
Blood Rev. 2007 Sep;21(5):245-53. doi: 10.1016/j.blre.2007.05.001. Epub 2007 Jun 21.
4
Epstein-Barr virus (EBV) latent membrane protein-1 down-regulates tumor necrosis factor-alpha (TNF-alpha) receptor-1 and confers resistance to TNF-alpha-induced apoptosis in T cells: implication for the progression to T-cell lymphoma in EBV-associated hemophagocytic syndrome.爱泼斯坦-巴尔病毒（EBV）潜伏膜蛋白1下调肿瘤坏死因子-α（TNF-α）受体1，并赋予T细胞对TNF-α诱导的凋亡的抗性：对EBV相关噬血细胞综合征进展为T细胞淋巴瘤的影响。
Am J Pathol. 2007 May;170(5):1607-17. doi: 10.2353/ajpath.2007.061026.
5
Lymphoma-associated hemophagocytic syndrome: clinical features and treatment outcome.淋巴瘤相关噬血细胞综合征：临床特征与治疗结果
Ann Hematol. 2007 Jul;86(7):493-8. doi: 10.1007/s00277-007-0278-6. Epub 2007 Mar 9.
6
Familial and acquired hemophagocytic lymphohistiocytosis.家族性和获得性噬血细胞性淋巴组织细胞增生症。
Eur J Pediatr. 2007 Feb;166(2):95-109. doi: 10.1007/s00431-006-0258-1. Epub 2006 Dec 7.
7
Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 15-2004. A 31-year-old man with bilateral testicular enlargement.
N Engl J Med. 2004 May 13;350(20):2081-7. doi: 10.1056/NEJMcpc049003.
8
NK and NK-like T-cell lymphoma in extranasal sites: a comparative clinicopathological study according to site and EBV status.鼻外部位的NK和NK样T细胞淋巴瘤：一项根据部位和EB病毒状态进行的比较临床病理研究
Histopathology. 2004 May;44(5):480-9. doi: 10.1111/j.1365-2559.2004.01867.x.
9
Human herpesvirus 8-associated hemophagocytic lymphohistiocytosis in human immunodeficiency virus-infected patients.人类免疫缺陷病毒感染患者中的人疱疹病毒8相关噬血细胞性淋巴组织细胞增生症
Clin Infect Dis. 2003 Jul 15;37(2):285-91. doi: 10.1086/375224. Epub 2003 Jul 1.
10
Non-Hodgkin's lymphoma of the testis: a retrospective study of 84 patients treated in the French anticancer centres.睾丸非霍奇金淋巴瘤：对法国抗癌中心治疗的84例患者的回顾性研究
Ann Oncol. 2001 Sep;12(9):1313-9. doi: 10.1023/a:1012224123385.
Zotero 插件