Department of Obstetrics and Gynecology, Sultan Qaboos University Hospital, Sultan Qaboos University College of Medicine, Muscat, Sultanate of Oman.
J Gynecol Oncol. 2012 Jul;23(3):201-4. doi: 10.3802/jgo.2012.23.3.201. Epub 2012 Jul 2.
Ovarian Sertoli-Leydig cell tumors are rare sex cord-stromal tumors, accounting for less than 1% of ovarian tumors. Majority of these tumors are benign and unilateral, only 3-5% are bilateral. These patients present with clinical features of virilization due to excessive secretion of testosterone from the tumor, however 50% may have no endocrine symptoms. We report a case of poorly differentiated Sertoli-Leydig cell tumour in a woman diagnosed during routine investigation of infertility. She had two spontaneous successful pregnancies after tumor excision laparoscopically.
卵巢 Sertoli-Leydig 细胞瘤是一种罕见的性索-间质肿瘤，占卵巢肿瘤的比例不到 1%。这些肿瘤大多数为良性和单侧的，只有 3-5%为双侧。由于肿瘤过度分泌睾酮，这些患者会出现男性化的临床表现，但 50%可能没有内分泌症状。我们报告了一例在常规不孕检查中诊断出的女性低分化 Sertoli-Leydig 细胞瘤病例。她在接受腹腔镜肿瘤切除术后成功自然妊娠两次。
