[在波兰，肠集聚性大肠杆菌是一个严重的临床问题吗？]
[Do enteroaggregative Escherichia coli is a significant clinical problem in Poland?].
作者信息
Wołkowicz Tomasz, Szych Jolanta
机构信息
Zakład Bakteriologii Narodowego Instytutu Zdrowia Publicznego-Pańistwowego Zakładu Higieny w Warszawie.
出版信息
Med Dosw Mikrobiol. 2012;64(1):63-71.
INTRODUCTION
Enteroaggregative Escherichia coli are poorly discovered pathogenic subgroup of these microorganism. They can cause watery diarrhea witch is often persistent. It seems that infections due to EAEC could comprise significant epidemiologic problem, covered especially children from developing countries and travelers visiting these countries.
METHODS
To find out, whether EAEC could comprise a problem in Poland, we examine 382 E. coli strains isolated from stool samples from patients with diarrhea in Poland in years 1997-2011. Three genes (aggR, aap and aat) were marked by Multiplex-PCR method.
RESULTS
Six of examined strains (1.5%) were marked as EAEC and they were isolated equally from children and adults.
CONCLUSIONS
It seems that EAEC could not comprise a significant problem in Poland but it should be taken in to account as a potential etiologic factor of diarrhea.
引言
肠聚集性大肠杆菌是这类微生物中发现较少的致病亚群。它们可引起常呈持续性的水样腹泻。似乎由肠聚集性大肠杆菌引起的感染可能构成重大的流行病学问题，尤其涉及发展中国家的儿童以及前往这些国家的旅行者。
方法
为了查明肠聚集性大肠杆菌在波兰是否会构成问题，我们检测了1997年至2011年期间从波兰腹泻患者粪便样本中分离出的382株大肠杆菌菌株。采用多重聚合酶链反应方法标记三个基因（aggR、aap和aat）。
结果
检测的菌株中有6株（1.5%）被标记为肠聚集性大肠杆菌，它们在儿童和成人中分离的数量相同。
结论
肠聚集性大肠杆菌似乎在波兰不会构成重大问题，但应将其视为腹泻的潜在病因加以考虑。
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