Bruls S, Radermecker M A, Creemers E, Bonnet P, Nellessen E, Van Damme H, De Leval L, Defraigne J O
Department of Cardiovascular Surgery, University Hospital of Liège, Belgium.
Acta Chir Belg. 2012 May-Jun;112(3):213-8.
Cardiovascular disease is the main cause of morbidity and mortality in patients with Marfan syndrome. The most life threatening complication is aortic root aneurysms leading to aortic dissection or rupture. It can be prevented by regular aortic follow-up and prophylactic aortic surgery. Modern aortic surgery has led to a substantial increase in the life expectancy of these patients. We report two cases of Marfan syndrome with cardiovascular complications. Their management is discussed according to the most recent literature.
心血管疾病是马凡综合征患者发病和死亡的主要原因。最危及生命的并发症是主动脉根部动脉瘤，可导致主动脉夹层或破裂。通过定期的主动脉随访和预防性主动脉手术可以预防。现代主动脉手术已使这些患者的预期寿命大幅提高。我们报告了两例患有心血管并发症的马凡综合征病例。根据最新文献对其治疗进行了讨论。
