• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

选择性微创冠状动脉搭桥术:分流还是环扎闭塞?评估围手术期左前降支分流对心肌损伤的保护作用。一项前瞻性随机研究。

Elective minimally invasive coronary artery bypass: shunt or tournique occlusion? Assessment of a protective role of perioperative left anterior descending shunting on myocardial damage. A prospective randomized study.

作者信息

Sorm Zdenek, Vojacek Jan, Cermakova Eva, Pudil Radek, Stock Ulrich A, Harrer Jan

机构信息

Department of Cardiac Surgery, Charles University in Prague, Faculty of Medicine in Hradec Kralove, University Hospital Hradec Kralove, Sokolska 581, 50005, Hradec Kralove, Czech Republic.

出版信息

J Cardiothorac Surg. 2012 Jul 18;7:69. doi: 10.1186/1749-8090-7-69.

DOI:10.1186/1749-8090-7-69
PMID:22809563
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3487851/
Abstract

BACKGROUND

To determine impact of intraluminal-left anterior descending shunt to prevent myocardial damage in minimally invasive coronary artery bypass.

METHODS

38 patients were randomly assigned to external tournique occlusion (n = 19) or intraluminal-left anterior descending shunt group (n= 19). Blood samples for cardiac troponin T were collected at 30 minutes prior to, 6 and 24 hours after surgery.

RESULTS

One patient in external tournique occlusion and two patients in intraluminal-left anterior descending shunt group were excluded from futher analysis due to preoperative cardiac troponin T level above the 99th-percentile. Postoperatively, each six patients in external tournique occlusion (33.3%) and intraluminal-left anterior descending shunt (35.3%) group were above the 99th-percentile. Two patients from each group (external tournique occlusion group 11.1% vs. intraluminal-left anterior descending shunt group 11.8%) had peak values above 10-% coeficient of variation cutoff (p = 1). There were no significant differences in between both groups at all studied timepoints.

CONCLUSION

There was no protective effect of intraluminal shunting on myocardial damage compared to short-term tournique occlusion. It is upon the surgeon's discretion which method may preferrably be used to achieve a bloodless field in grafting of the non-occluded left anterior descending in minimally invasive coronary artery bypass.

摘要

背景

确定在微创冠状动脉旁路移植术中使用左前降支腔内分流术预防心肌损伤的效果。

方法

38例患者被随机分为体外阻断组(n = 19)和左前降支腔内分流组(n = 19)。在手术前30分钟、术后6小时和24小时采集心肌肌钙蛋白T血样。

结果

由于术前心肌肌钙蛋白T水平高于第99百分位数,体外阻断组的1例患者和左前降支腔内分流组的2例患者被排除在进一步分析之外。术后,体外阻断组和左前降支腔内分流组各有6例患者(分别为33.3%和35.3%)高于第99百分位数。每组各有2例患者(体外阻断组为11.1%,左前降支腔内分流组为11.8%)峰值高于10-%变异系数临界值(p = 1)。在所有研究时间点,两组之间均无显著差异。

结论

与短期阻断相比,腔内分流术对心肌损伤没有保护作用。在微创冠状动脉旁路移植术中,对于非阻塞性左前降支进行移植时,采用哪种方法能更好地实现无血视野,由外科医生自行决定。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfad/3487851/843a650d5f07/1749-8090-7-69-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfad/3487851/843a650d5f07/1749-8090-7-69-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/bfad/3487851/843a650d5f07/1749-8090-7-69-1.jpg

相似文献

1
Elective minimally invasive coronary artery bypass: shunt or tournique occlusion? Assessment of a protective role of perioperative left anterior descending shunting on myocardial damage. A prospective randomized study.选择性微创冠状动脉搭桥术:分流还是环扎闭塞?评估围手术期左前降支分流对心肌损伤的保护作用。一项前瞻性随机研究。
J Cardiothorac Surg. 2012 Jul 18;7:69. doi: 10.1186/1749-8090-7-69.
2
Occlusion versus shunting during MIDCAB: effects on left ventricular function and quality of anastomosis.微创冠状动脉搭桥术中的阻断与分流:对左心室功能及吻合质量的影响
Ann Thorac Surg. 2002 May;73(5):1418-23. doi: 10.1016/s0003-4975(02)03472-0.
3
Is chronic total coronary occlusion a risk factor for long-term outcome after minimally invasive bypass grafting of the left anterior descending artery?慢性完全闭塞性冠状动脉病变是否是微创左前降支旁路移植术后长期预后的危险因素?
Ann Thorac Surg. 2010 May;89(5):1496-501. doi: 10.1016/j.athoracsur.2010.01.063.
4
Intracoronary shunt insertion prevents myocardial stunning in a juvenile porcine MIDCAB model absent of coronary artery disease.在无冠状动脉疾病的幼年猪非体外循环冠状动脉搭桥术模型中,冠状动脉内分流器的植入可预防心肌顿抑。
Eur J Cardiothorac Surg. 1999 Feb;15(2):173-8; discussion 178-9. doi: 10.1016/s1010-7940(98)00290-5.
5
A Novel Approach Using Computed Tomography Angiograms to Predict Sternotomy or Complicated Anastomosis in Patients Undergoing Robotically Assisted Minimally Invasive Direct Coronary Artery Bypass.一种利用计算机断层血管造影预测接受机器人辅助微创直接冠状动脉旁路移植术患者胸骨切开术或复杂吻合术的新方法。
Innovations (Phila). 2018 May/Jun;13(3):207-210. doi: 10.1097/IMI.0000000000000499.
6
Initial experience using an intraluminal shunt during revascularization of the beating heart.在跳动心脏血管重建术中使用腔内分流器的初步经验。
Ann Thorac Surg. 1997 Jun;63(6):1742-7. doi: 10.1016/s0003-4975(97)00361-5.
7
Experimental evidence of regional myocardial ischemia during beating heart coronary bypass: prevention with temporary intraluminal shunts.
Heart Surg Forum. 2002;6(1):10-8. doi: 10.1532/hsf.869.
8
Minimally invasive single-vessel left internal mammary to left anterior descending artery bypass grafting improves outcomes over conventional sternotomy: A single-institution retrospective cohort study.微创单支血管左乳内动脉至左前降支动脉搭桥术比传统胸骨切开术能改善预后:一项单机构回顾性队列研究。
J Card Surg. 2019 Sep;34(9):788-795. doi: 10.1111/jocs.14144. Epub 2019 Jul 3.
9
Minimally invasive hybrid coronary artery revascularization.微创杂交冠状动脉血运重建术。
Ann Thorac Surg. 2008 Dec;86(6):1856-60. doi: 10.1016/j.athoracsur.2008.08.034.
10
Left anterior descending coronary artery bypass grafting through minimal thoracotomy.
Ann Thorac Surg. 1998 Sep;66(3):1008-11. doi: 10.1016/s0003-4975(98)00658-4.

引用本文的文献

1
Intraoperative transit time flow measurements during off-pump coronary artery bypass surgery: The impact of coronary stenosis on competitive flow.非体外循环冠状动脉旁路移植术中的术中跨时间流量测量:冠状动脉狭窄对竞争血流的影响。
J Card Surg. 2022 Feb;37(2):305-313. doi: 10.1111/jocs.16103. Epub 2021 Oct 21.

本文引用的文献

1
Intracoronary shunt prevents ischemia in off-pump coronary artery bypass surgery.冠状动脉内分流术可预防非体外循环冠状动脉搭桥手术中的缺血情况。
Ann Thorac Surg. 2009 Jan;87(1):54-60. doi: 10.1016/j.athoracsur.2008.08.032.
2
Shunt or snare: coronary endothelial damage due to hemostatic devices for beating heart coronary surgery.
Ann Thorac Surg. 2008 Dec;86(6):1873-7. doi: 10.1016/j.athoracsur.2008.06.047.
3
Reference population and marathon runner sera assessed by highly sensitive cardiac troponin T and commercial cardiac troponin T and I assays.通过高敏心肌肌钙蛋白T以及商用心肌肌钙蛋白T和I检测法评估参考人群和马拉松运动员血清。
Clin Chem. 2009 Jan;55(1):101-8. doi: 10.1373/clinchem.2008.106427. Epub 2008 Nov 6.
4
Influence of intracoronary shunt on myocardial damage: a prospective randomized study.冠状动脉内分流对心肌损伤的影响:一项前瞻性随机研究。
Eur J Cardiothorac Surg. 2008 Nov;34(5):1000-4. doi: 10.1016/j.ejcts.2008.08.002. Epub 2008 Sep 9.
5
Intracoronary shunt versus bulldog clamp in off-pump bypass surgery. Endothelial trauma: shunt versus clamp.非体外循环冠状动脉搭桥手术中冠状动脉内分流器与阻断钳的比较。内皮损伤:分流器与阻断钳的比较。
J Surg Res. 2008 Dec;150(2):261-5. doi: 10.1016/j.jss.2007.12.774. Epub 2008 Jan 16.
6
Universal definition of myocardial infarction.心肌梗死的通用定义。
Circulation. 2007 Nov 27;116(22):2634-53. doi: 10.1161/CIRCULATIONAHA.107.187397. Epub 2007 Oct 19.
7
National Academy of Clinical Biochemistry and IFCC Committee for Standardization of Markers of Cardiac Damage Laboratory Medicine Practice Guidelines: analytical issues for biochemical markers of acute coronary syndromes.美国国家临床生物化学学会和国际临床化学与检验医学联合会心脏损伤标志物标准化委员会实验室医学实践指南:急性冠状动脉综合征生化标志物的分析问题
Clin Chem. 2007 Apr;53(4):547-51. doi: 10.1373/clinchem.2006.084715. Epub 2007 Mar 23.
8
A meta-analysis of randomized control trials comparing minimally invasive direct coronary bypass grafting versus percutaneous coronary intervention for stenosis of the proximal left anterior descending artery.一项比较微创直接冠状动脉搭桥术与经皮冠状动脉介入治疗左前降支近端狭窄的随机对照试验的荟萃分析。
Eur J Cardiothorac Surg. 2007 Apr;31(4):691-7. doi: 10.1016/j.ejcts.2007.01.018. Epub 2007 Feb 14.
9
Intracoronary shunt reduces postoperative troponin leaks: a prospective randomized study.冠状动脉内分流术可减少术后肌钙蛋白泄漏:一项前瞻性随机研究。
Eur J Cardiothorac Surg. 2006 Feb;29(2):186-9. doi: 10.1016/j.ejcts.2005.11.014. Epub 2006 Jan 11.
10
Troponin: the biomarker of choice for the detection of cardiac injury.肌钙蛋白:用于检测心脏损伤的首选生物标志物。
CMAJ. 2005 Nov 8;173(10):1191-202. doi: 10.1503/cmaj/051291.