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左心室肥厚中的电重构——对于诊断左心室肥厚的多种心电图标准,是否存在一个统一的假说?

Electrical remodeling in left ventricular hypertrophy-is there a unifying hypothesis for the variety of electrocardiographic criteria for the diagnosis of left ventricular hypertrophy?

作者信息

Rodriguez-Padial Luis, Bacharova Ljuba

机构信息

Cardiac Unit, Complejo Hospitalario de Toledo, Avda. Barber 30, 45005, Toledo, Spain.

出版信息

J Electrocardiol. 2012 Sep;45(5):494-7. doi: 10.1016/j.jelectrocard.2012.06.003. Epub 2012 Jul 17.

DOI:10.1016/j.jelectrocard.2012.06.003
PMID:22809575
Abstract

Although electrocardiography has been used to estimate left ventricular hypertrophy and to obtain useful prognostic information in different clinical settings, its correlation with left ventricular mass is poor and, therefore, its sensitivity and specificity for the diagnosis of left ventricylar hypertrophy are low. Experimental work has demonstrated that the increase in voltage and duration of the QRS complex of the electrocardiogram are not only related to left ventricular mass but also to changes in the electrophysiological properties of the myocardium. Therefore, a new strategy is needed to use electrocardiography not to estimate left ventricular mass but aimed to add useful prognostic information.

摘要

尽管心电图已被用于评估左心室肥厚,并在不同临床环境中获取有用的预后信息,但其与左心室质量的相关性较差,因此,其诊断左心室肥厚的敏感性和特异性较低。实验研究表明,心电图QRS波群电压和时限的增加不仅与左心室质量有关,还与心肌电生理特性的变化有关。因此,需要一种新的策略来利用心电图,不是用于评估左心室质量,而是旨在增加有用的预后信息。

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引用本文的文献

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Circ Arrhythm Electrophysiol. 2016 Apr;9(4):e003629. doi: 10.1161/CIRCEP.115.003629.
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Electrocardiogram Derived QRS Duration >120 ms is Associated With Elevated Plasma Homocysteine Levels in a Rural Australian Cross-Sectional Population.在澳大利亚农村横断面人群中,心电图衍生的QRS波时限>120毫秒与血浆同型半胱氨酸水平升高相关。
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Development of metabolic syndrome and electrocardiographic features of left ventricular hypertrophy in middle-aged working subjects.
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