Toll Edward C, Nunez Desmond A
University College London Ear Institute, Southmead Hospital, Bristol, UK.
J Laryngol Otol. 2012 Oct;126(10):976-83. doi: 10.1017/S0022215112001326. Epub 2012 Jul 19.
Acute otitis media is very common, but diagnostic criteria and treatment recommendations vary considerably.
Medline, the Cochrane Database of Systematic Reviews and the Cochrane Central Register of Controlled Trials were searched using the key words 'acute otitis media' AND 'diagnosis' OR 'diagnostic criteria' OR 'definition', and by combining the terms 'acute otitis media' AND 'guidelines'. PubMed was searched using the key words 'mastoiditis' and 'prevalence'.
The 11 most recently published guidelines unanimously agreed that adequate analgesia should be prescribed in all cases. The majority recommended that routine antibiotic prescription should be avoided in mild to moderate cases and when there was diagnostic uncertainty in patients two years and older. Antibiotics were recommended in children two years and younger, most commonly a 5-day course of amoxicillin (or a macrolide in patients allergic to penicillin).
Level 1A evidence shows that selected cases of acute otitis media benefit from antibiotic prescription.
急性中耳炎非常常见,但诊断标准和治疗建议差异很大。
使用关键词“急性中耳炎”和“诊断”或“诊断标准”或“定义”,并结合“急性中耳炎”和“指南”等术语,检索了医学文献数据库(Medline)、Cochrane系统评价数据库和Cochrane对照试验中心注册库。使用关键词“乳突炎”和“患病率”检索了PubMed。
最近发表的11项指南一致认为,所有病例均应给予充分的镇痛治疗。大多数指南建议,在轻度至中度病例以及2岁及以上患者诊断存在不确定性时,应避免常规使用抗生素。建议对2岁及以下儿童使用抗生素,最常用的是5天疗程的阿莫西林(对青霉素过敏的患者使用大环内酯类药物)。
1A级证据表明,部分急性中耳炎病例可从抗生素治疗中获益。