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急性中耳炎观察等待疗法的概念与实践

The concept and practice of a wait-and-see approach to acute otitis media.

作者信息

Spiro David M, Arnold Donald H

机构信息

Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.

出版信息

Curr Opin Pediatr. 2008 Feb;20(1):72-8. doi: 10.1097/MOP.0b013e3282f2fa62.

Abstract

PURPOSE OF REVIEW

We review the contemporary management of acute otitis media, including symptomatic care, the rationale and literature for utilizing the wait-and-see approach, and the indications for immediate therapy with antibiotics.

RECENT FINDINGS

Current guidelines recommend selective use of observation in children diagnosed with acute otitis media. Recent evidence suggests that a wait-and-see approach will reduce the use of antibiotics and decrease adverse events associated with their use. Earlier studies found that antimicrobials reduce pain and discomfort in the acute phase of illness compared with placebo. A recently published trial, however, suggests that when analgesics are utilized there may be minimal or no difference in otalgia whether antibiotics are prescribed or withheld.

SUMMARY

Treatment of acute otitis media is the most frequent indication for prescribing antibiotics in the pediatric population. Evidence suggests there is marginal benefit from antibiotics for most children diagnosed with AOM. Based on current data, we propose an algorithm for the management of children with AOM that includes a wait-and-see approach with specific indications for immediate treatment with antibiotics. A wait-and-see approach to acute otitis media that empowers families by using a shared decision-making model will reduce the use of antibiotics and will decrease resistance to antimicrobials.

摘要

综述目的

我们回顾急性中耳炎的现代治疗方法,包括对症治疗、采用观察等待方法的基本原理和文献,以及立即使用抗生素治疗的指征。

最新发现

当前指南建议对诊断为急性中耳炎的儿童选择性地采用观察等待方法。近期证据表明,观察等待方法将减少抗生素的使用,并减少与其使用相关的不良事件。早期研究发现,与安慰剂相比,抗菌药物在疾病急性期可减轻疼痛和不适。然而,最近发表的一项试验表明,当使用镇痛药时,无论是否使用抗生素,耳痛可能极小或没有差异。

总结

急性中耳炎的治疗是儿科人群中最常见的使用抗生素的指征。证据表明,对于大多数诊断为急性中耳炎的儿童,抗生素的益处微乎其微。基于当前数据,我们提出了一种针对急性中耳炎儿童的管理算法,其中包括观察等待方法以及立即使用抗生素治疗的具体指征。通过采用共同决策模型让家庭参与其中的急性中耳炎观察等待方法,将减少抗生素的使用,并降低对抗菌药物的耐药性。

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