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[小鼠中突变型安哥拉-Y基因表达的分析]

[An analysis of the expression of the mutant angora-Y gene in the mouse].

作者信息

Koniukhov B V, Berdaliev A S

出版信息

Ontogenez. 1990 Sep-Oct;21(5):502-7.

PMID:2280969
Abstract

We studied the rate and duration of the growth of G1 and G3 hairs in mice homozygous for angora-Y mutant gene (goY). The follicular diameter of G3 hairs and the growth rate of G1 and G3 hairs in goY/goY mice do not differ from normal. However, the duration of growth period of all four studied types of hairs in goY/goY mice is longer than in the normal phenotype. Growth of the guard hairs G1 and G3 in mutants continues longer than in the normal phenotype by 7 and 3 days, respectively. For other hair types G1 and G3 (awl, auchene, zigzag) the duration of the growth period is approximately 3 days longer than in the control. As a result in goY/goY mice guard hairs G1 and G3 which have completed growth are 2 and 1.5 times longer than in +/+ mice. Other types of G1 hairs in mutants are longer by 50% and G3 hairs by 30% than in the wild type.

摘要

我们研究了安哥拉 - Y突变基因(goY)纯合小鼠中G1和G3毛发的生长速率和持续时间。goY/goY小鼠中G3毛发的毛囊直径以及G1和G3毛发的生长速率与正常小鼠并无差异。然而,goY/goY小鼠中所有四种研究类型毛发的生长期持续时间比正常表型的小鼠更长。突变体中G1和G3的针毛生长持续时间分别比正常表型的小鼠长7天和3天。对于其他毛发类型G1和G3(刚毛、触须毛、之字形毛),其生长期持续时间比对照组大约长3天。结果,在goY/goY小鼠中,已完成生长的G1和G3针毛比+/+小鼠中的长2倍和1.5倍。突变体中其他类型的G1毛发比野生型长50%,G3毛发长30%。

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