Department of Orthopaedic Surgery, Greenville Hospital System University Medical Center, 701 Grove Road, Greenville, SC 29605, USA.
J Bone Joint Surg Am. 2012 Jul 18;94 Suppl 1:15-8. doi: 10.2106/JBJS.L.00180.
A pilot randomized study is often essential to ensure the feasibility of conducting a large, randomized study. Pilot studies help to define the sample size, establish measurable outcomes, promote methodological rigor, establish the ability to recruit participants, assess the risk-benefit ratio of the treatments, and evaluate the economic viability of a definitive study.
一项初步的随机研究通常是至关重要的，以确保进行大型随机研究的可行性。初步研究有助于确定样本量，建立可衡量的结果，提高方法学的严谨性，建立招募参与者的能力，评估治疗方法的风险效益比，并评估确定性研究的经济可行性。
