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多发性硬化症的诊断与鉴别诊断

Diagnosis and differential diagnosis of multiple sclerosis.

作者信息

Cree Bruce A C

出版信息

Continuum (Minneap Minn). 2010 Oct;16(5 Multiple Sclerosis):19-36. doi: 10.1212/01.CON.0000389932.38919.c7.

DOI:10.1212/01.CON.0000389932.38919.c7
PMID:22810596
Abstract

No single test to diagnose multiple sclerosis is available, and its cause is unknown. The diagnosis relies on recognition of the clinical patterns of the disease as well as exclusion of other possible mimics. Waxing and waning neurologic deficits that localize to the CNS are the hallmark of the disease in most patients. The diagnosis can be supported by laboratory studies, including MRI of the brain and spinal cord, analysis of CSF, and evoked-potential studies of the visual and somatosensory pathways.

摘要

目前尚无单一的测试可用于诊断多发性硬化症,其病因也尚不清楚。诊断依赖于对该疾病临床模式的识别以及排除其他可能的类似疾病。在大多数患者中,累及中枢神经系统且症状时轻时重的神经功能缺损是该疾病的标志。实验室检查,包括脑部和脊髓的磁共振成像(MRI)、脑脊液分析以及视觉和躯体感觉通路的诱发电位研究,可为诊断提供支持。

相似文献

1
Diagnosis and differential diagnosis of multiple sclerosis.多发性硬化症的诊断与鉴别诊断
Continuum (Minneap Minn). 2010 Oct;16(5 Multiple Sclerosis):19-36. doi: 10.1212/01.CON.0000389932.38919.c7.
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Magnetic resonance imaging in isolated noncompressive spinal cord syndromes.孤立性非压迫性脊髓综合征的磁共振成像
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Failure to develop multiple sclerosis in patients with neurologic symptoms without objective evidence.在没有客观证据的情况下,患有神经系统症状的患者未发展为多发性硬化症。
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Are somatosensory evoked potentials of the tibial nerve the most sensitive test in diagnosing multiple sclerosis?胫神经体感诱发电位是诊断多发性硬化症最敏感的检查吗?
Neurol India. 2010 Jul-Aug;58(4):537-41. doi: 10.4103/0028-3886.68669.
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[Syringomyelia, a neglected differential diagnosis in multiple sclerosis. 6 cases from a specialty clinic for multiple sclerosis].
Nervenarzt. 1995 Aug;66(8):630-3.
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Childhood multiple sclerosis (MS): multimodal evoked potentials (EP) and magnetic resonance imaging (MRI) comparative study.儿童多发性硬化症(MS):多模式诱发电位(EP)与磁共振成像(MRI)对比研究。
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The role of MRI in the diagnosis of multiple sclerosis.磁共振成像在多发性硬化诊断中的作用。
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