Mukhomedzianova L V, Andriianova I V, Kashirtseva I A
Vestn Otorinolaringol. 2012(2):61-2.
The purpose of this work was to evaluate the efficacy of the prevention of recurrent respiratory infections with the use of the immunomodulatory respiratory spray (IRS-19). The study involved 60 children at the age from 4 to 7 years allocated to three groups. Group 1 was comprised of 20 children treated by two daily irrigation of nasal sinuses with a seawater solution. Group 2 included 20 children treated by irrigation of nasal sinuses with IRS-19 twice daily during 2 weeks.. Group 3 consisted of 20 children treated by irrigation of nasal sinuses with a saline solution and topical immunostimulator IRS-19 twice daily. It was shown that therapy with IRS-19 resulted in a more than two-fold reduction in the frequency of relapses of the acute respiratory infections as compared with control.
这项工作的目的是评估使用免疫调节呼吸道喷雾剂（IRS - 19）预防反复呼吸道感染的疗效。该研究涉及60名4至7岁的儿童，他们被分为三组。第一组由20名儿童组成，每天用海水溶液冲洗鼻窦两次进行治疗。第二组包括20名儿童，在两周内每天用IRS - 19冲洗鼻窦两次进行治疗。第三组由20名儿童组成，每天用盐溶液和局部免疫刺激剂IRS - 19冲洗鼻窦两次进行治疗。结果表明，与对照组相比，使用IRS - 19治疗使急性呼吸道感染复发频率降低了两倍多。
