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单绒毛膜双胎妊娠无并发症时的分娩方式及新生儿结局

Mode of delivery and neonatal outcome in uncomplicated monochorionic twin pregnancies.

作者信息

Weisz Boaz, Hogen Liat, Yinon Yoav, Mazaki Shali, Gindes Liat, Schiff Eyal, Lipitz Shlomo

机构信息

Department of Obstetrics and gynecology, Sheba Medical Center , Tel-Hashomer 52621 , Israel and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.

出版信息

J Matern Fetal Neonatal Med. 2012 Dec;25(12):2721-4. doi: 10.3109/14767058.2012.712560. Epub 2012 Aug 22.

Abstract

OBJECTIVE

The association between of mode of delivery and perinatal morbidity in monochorionic (MC) twins is not clear. Thus there is no agreement regarding the optimal mode of delivery of MC twins. The aim of this study is to determine the impact of the mode of delivery on neonatal outcome of uncomplicated MC twins in a tertiary center with a strict policy of delivering MC twins by 37 weeks' gestation.

METHODS

Retrospective analysis of all uncomplicated MC twin deliveries at a tertiary referral hospital during a 5-year period. Complicated MC pregnancies (fetal death, selective reduction, twin to twin transfusion syndrome, fetal growth restriction of one or both twins or major fetal anomalies) were excluded. Induction of labor or planned caesarean sections of uncomplicated MC pregnancies was conducted between 35 and 37 weeks of gestation. Neonatal outcomes of MC twins were compared according to the mode of delivery. Moreover, mode of delivery was compared with a control group of 1934 dichorionic (DC) twin pregnancies delivered during the same period.

RESULTS

The rate of Caesarean section was 63.4% in uncomplicated MC/DA twins pregnancies and this was similar to our rate in DC twins (61%, p = 0.65). Multivariate analysis revealed that adverse neonatal outcome was significantly associated with gestational age at delivery, neonatal birth weight discordance and male gender but not with the intended or actual mode of delivery.

CONCLUSION

Delivering MC twin pregnancies by 37 weeks' gestation is associated with similar rate of vaginal deliveries compared with DC twin pregnancies. The neonatal outcome was not affected by the mode of delivery, and therefore vaginal delivery seems safe in MC twins.

摘要

目的

单绒毛膜(MC)双胎的分娩方式与围产期发病率之间的关联尚不清楚。因此,对于MC双胎的最佳分娩方式尚无共识。本研究的目的是在一家三级中心确定分娩方式对无并发症的MC双胎新生儿结局的影响,该中心有在孕37周时分娩MC双胎的严格政策。

方法

对一家三级转诊医院5年内所有无并发症的MC双胎分娩进行回顾性分析。排除复杂的MC妊娠(胎儿死亡、选择性减胎、双胎输血综合征、一个或两个胎儿生长受限或严重胎儿畸形)。在妊娠35至37周之间对无并发症的MC妊娠进行引产或计划剖宫产。根据分娩方式比较MC双胎的新生儿结局。此外,将分娩方式与同期分娩的1934例双绒毛膜(DC)双胎妊娠的对照组进行比较。

结果

无并发症的MC/双羊膜囊(DA)双胎妊娠剖宫产率为63.4%,与我们DC双胎的剖宫产率相似(61%,p = 0.65)。多因素分析显示,不良新生儿结局与分娩时的孕周、新生儿出生体重差异和男性性别显著相关,而与预期或实际分娩方式无关。

结论

与DC双胎妊娠相比,在孕37周时分娩MC双胎妊娠的阴道分娩率相似。新生儿结局不受分娩方式的影响,因此阴道分娩对MC双胎似乎是安全的。

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