Selikhova Marianna, Scott Catherine, Silva Mark, Rugg-Gunn Furgus
Department of Movement Disorders, National Hospital for Neurology and Neurosurgery, London, UK.
BMJ Case Rep. 2012 Jul 19;2012:bcr2012006247. doi: 10.1136/bcr-2012-006247.
A 20-year-old ambidextrous female student with a 15-year history of refractory seizures was admitted to the epilepsy department for a second opinion on her diagnosis and treatment. She developed frequent motor paroxysms at the age of 4-5 years, which appeared resistant to antiepileptic therapy and which have continued to the present day. Over the last 8 years she also had five generalised tonic-clonic seizures. There is a family history of epilepsy on the maternal side. The first type of episode is characterised by left-hand flickering, associated with head turning and loss of awareness. During the second type of attack the patient demonstrates vigorous hand biting which starts without warning. The patient appears disorientated subsequently. EEG telemetry was performed and confirmed the diagnosis of both epilepsy and non-epileptic attacks. Literature reports of the relevant cases are discussed.
一名20岁的双手灵活的女学生,有15年难治性癫痫发作史,因对其诊断和治疗寻求第二种意见而入住癫痫科。她在4至5岁时出现频繁的运动性发作,这些发作似乎对抗癫痫治疗有抵抗性,并且一直持续到现在。在过去8年里,她还发生了5次全身性强直阵挛发作。母亲一方有癫痫家族史。第一种发作类型的特征是左手颤动,伴有头部转动和意识丧失。在第二种发作期间,患者会毫无预兆地开始剧烈咬手。患者随后会出现定向障碍。进行了脑电图遥测,证实了癫痫和非癫痫发作的诊断。讨论了相关病例的文献报道。