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社交互动期间实验室雄性小鼠睾丸功能的改变:雌性存在的影响。

Modification of the testicular function in laboratory male mice during social interactions: effect of female presence.

作者信息

Kleshev M A, Osadchuk L V

机构信息

Laboratory of Endocrinologic Genetics, Institute of Cytology and Genetics, the Russian Academy of Sciences, Novosibirsk, Russia.

出版信息

Bull Exp Biol Med. 2012 Jun;153(2):240-3. doi: 10.1007/s10517-012-1686-8.

Abstract

The count of spermatozoa in both caudal epididymides, percentage of abnormal spermatozoon heads and of mobile spermatozoa, body weight, weights of the testes and caudal epididymides were evaluated in adult inbred males (PT and CBA/Lac) kept with females for 5 days. Male mice of the same genotypes and age separated from females served as controls. In males kept with females, the weights of the testes increased in PT male mice, the percentage of rapidly mobile spermatozoa increased in CBA/Lac mice, and body weights decreased in males of both genotypes. The morphometric and spermatogenic parameters in laboratory mice were modulated by the presence of a female, but the effect was determined by the male genotype.

摘要

对与雌性小鼠共同饲养5天的成年近交系雄性小鼠(PT和CBA/Lac)双侧附睾尾中的精子计数、异常精子头部百分比和活动精子百分比、体重、睾丸和附睾尾重量进行了评估。将相同基因型和年龄的雄性小鼠与雌性小鼠分开作为对照。在与雌性小鼠共同饲养的雄性小鼠中,PT雄性小鼠的睾丸重量增加,CBA/Lac小鼠中快速活动精子的百分比增加,两种基因型的雄性小鼠体重均下降。雌性小鼠的存在调节了实验室小鼠的形态计量学和生精参数,但这种影响由雄性基因型决定。

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