Holbrook C T, Crist W M, Kohaut E C, Buntain W L
Med Pediatr Oncol. 1979;7(2):117-21. doi: 10.1002/mpo.2950070204.
A six-year-old girl presented with clinical signs and symptoms of right-sided heart failure. Cardiac catheterization demonstrated filling defects in both pulmonary arteries felt to represent metastatic lesions or thromboemboli. Intravenous pyelogram revealed bilateral renal masses and intrarenal obstruction. Acute renal failure was unresponsive to standard therapy. An open renal biopsy revealed Wilms tumor with favorable histology. Aggressive chemotherapy and irradiation were undertaken and renal function returned. This case adds to the heterogeneity of presentations described for Wilms tumor, and review of the literature reveals no other cases with similar presenting signs.
一名六岁女孩出现右侧心力衰竭的临床体征和症状。心导管检查显示双侧肺动脉充盈缺损，考虑为转移性病变或血栓栓塞。静脉肾盂造影显示双侧肾肿块和肾内梗阻。急性肾衰竭对标准治疗无反应。开放性肾活检显示为组织学良好的肾母细胞瘤。进行了积极的化疗和放疗，肾功能恢复。该病例增加了肾母细胞瘤所描述表现的异质性，文献回顾显示没有其他具有类似表现体征的病例。
