Suppr超能文献

预防:我们能否在问题出现之前阻止它们?

Prevention: can we stop problems before they arise?

机构信息

College of Podiatric Medicine, Western University of the Health Sciences, Pomona, CA 91766-1854, USA.

出版信息

Semin Vasc Surg. 2012 Jun;25(2):122-8. doi: 10.1053/j.semvascsurg.2012.05.002.

Abstract

It is estimated that 50% of diabetic ulcerations and amputations can be prevented by identifying the at-risk foot and implementing preventative strategies. Patients with diabetes mellitus (DM) should be screened and placed in the appropriate risk category. Risk factors for the development of ulcer in several prospective studies include neuropathy, deformity, limited joint mobility, vascular disease, and history of previous ulceration or amputation. Early identification of the at-risk foot and placing the patient in the appropriate risk category is essential to prevention. Once the at-risk foot is identified, abnormal foot pressures should be reduced or eliminated using several treatment options. Repetitive, moderate mechanical stress (the pressure time integral) is often the initial mechanism of injury in the formation and/or recurrence of diabetic foot ulcers. Once conservative treatment options to off load the foot have failed, surgery should be considered. There are patients with diabetic foot ulcers for whom a combination of surgery (intrinsic off loading) and extrinsic off loading is better than either method alone. These difficult wounds are characterized by a combination of variables acting singularly or together, such as neuropathy, rigid deformity, limited joint mobility, and activity level. Our experience dictates, patients with rigid deformity and limited joint mobility get caught in the cycle of repetitive stress and cannot break the cycle until the etiology of the structural deformity is addressed surgically and preventative strategies for off loading, temperature monitoring, and activity level are implemented. If a structural deformity exists, the deformity will delay or prevent healing of the ulcer. Once the ulcer is healed, the likelihood for recurrence is high unless the deformity is corrected. When a structural deformity exists, the patient should be referred for evaluation and possible prophylactic surgery.

摘要

据估计,通过识别高危足部并实施预防策略,可以预防 50%的糖尿病溃疡和截肢。糖尿病患者应进行筛查并归入适当的风险类别。在几项前瞻性研究中,溃疡发生的危险因素包括神经病变、畸形、关节活动度受限、血管疾病以及既往溃疡或截肢史。早期识别高危足部并将患者归入适当的风险类别对于预防至关重要。一旦识别出高危足部,就应使用多种治疗选择来降低或消除异常足部压力。反复、适度的机械应力(压力时间积分)通常是糖尿病足溃疡形成和/或复发的初始损伤机制。一旦足部减压的保守治疗方法失败,就应考虑手术。对于某些糖尿病足溃疡患者,手术(内在减压)和外在减压的结合优于单独使用任何一种方法。这些困难的伤口的特点是多种变量单独或共同作用,如神经病变、僵硬畸形、关节活动度受限和活动水平。我们的经验表明,患有僵硬畸形和关节活动度受限的患者会陷入反复应力的循环中,除非手术解决结构畸形的病因,并实施减压、温度监测和活动水平的预防策略,否则无法打破这种循环。如果存在结构性畸形,畸形将延迟或阻止溃疡愈合。一旦溃疡愈合,如果不纠正畸形,复发的可能性很高。当存在结构性畸形时,应将患者转介进行评估和可能的预防性手术。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验