de Vries C, Vanhaesebrouck E, Govaere J, Hoogewijs M, Bosseler L, Chiers K, Ducatelle R
Department of Pathology, Bacteriology and Avian Diseases, College of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke Ghent, Belgium.
J Comp Pathol. 2013 Feb;148(2-3):214-9. doi: 10.1016/j.jcpa.2012.05.017. Epub 2012 Jul 20.
A premature dead equine fetus with excessive fluctuating distension of the abdomen was delivered by extraction. Post-mortem examination revealed ascites and a solitary, irregular, bulging, multinodular, firm, yellow mass of 25 cm in diameter in the right liver lobe. Extensive peritoneal implantation metastases were present. The masses were composed of polygonal embryonal cells arranged in sheets and nests. Based on the immunohistochemical expression of Ki67, low molecular weight cytokeratin and alpha-1 fetoprotein, a diagnosis of hepatoblastoma with peritoneal implantation metastases was made.
通过牵引取出一匹早产死亡的马胎儿，其腹部有过度的波动性膨隆。尸检发现有腹水，右肝叶有一个直径25厘米、孤立、不规则、凸起、多结节、坚实、黄色的肿块。存在广泛的腹膜种植转移。肿块由排列成片和巢状的多边形胚胎细胞组成。根据Ki67、低分子量细胞角蛋白和甲胎蛋白的免疫组化表达，诊断为伴有腹膜种植转移的肝母细胞瘤。
