Ishiko Takatoshi, Inomata Yukihiro, Beppu Toru, Asonuma Katuhiro, Okajima Hideki, Takeiti Takayuki, Tikamoto Akira, Yamamoto Hidekazu, Baba Hideo
Department of Gastroenterological Surgery, Graduate School of Medicine, Kumamoto University, Kumamoto, Japan.
Hepatogastroenterology. 2012 Sep;59(118):1907-10. doi: 10.5754/hge10088.
BACKGROUND/AIMS: In LDLT, parechymal resection is the most invasive process in the donor procedure. The control of bleeding is crucial for donor safety without the occlusion of hepatic inflow. Therefore, a reliable coagulation device is necessary for the transection of the hepatic parenchyma. This study evaluated a newly developed monopolar applicator, SOFT COAG (ERBE Elektromedizin, Tübingen) for rapid soft coagulation with regulated power output. Our objective was to assess an improved hepatic resection technique using a the SOFT COAG device for LDLT.
Between July 1999 and May 2008, 195 consecutive donors underwent a hepatic resection for LDLT. For graft extraction, 50 patients had a left lateral sectionectomy (LLS), 65 had a left hemihepatectomy (LHH), and 80 had a right hemihepatectomy (RHH).
In 125 donors, the control of parenchymal bleeding was performed by coagulation with bipolar forceps and in 70 donors it was controlled by soft coagulation with a monopolar electrode. The intraoperative blood loss was 763.9±494.4 mL and 435.2±424.7mL in RHH with bipolar and soft coagulation, respectively, with a statistically significant difference. Regarding postoperative liver function, most of the laboratory data showed no significant difference according to coagulation device. There was no significant difference in the incidence of postoperative complications.
It is evident that the new soft coagulation device represents a safe and feasible technique for donor hepatic parenchymal transection without inflow occlusion.
背景/目的:在活体肝移植(LDLT)中,肝实质切除是供体手术中创伤最大的步骤。在不阻断肝血流的情况下控制出血对供体安全至关重要。因此,在肝实质横断时需要一种可靠的凝血装置。本研究评估了一种新开发的单极电凝器SOFT COAG(德国爱尔博电子医疗公司,图宾根),其具有功率输出可调节的快速软凝功能。我们的目的是评估使用SOFT COAG装置进行LDLT的改良肝切除技术。
1999年7月至2008年5月,195例连续供体接受了LDLT肝切除术。为了获取移植物,50例患者进行了左外叶切除术(LLS),65例进行了左半肝切除术(LHH),80例进行了右半肝切除术(RHH)。
125例供体通过双极钳凝血控制肝实质出血,70例供体通过单极电极软凝控制出血。右半肝切除术中,双极凝血组术中失血量为763.9±494.4 mL,软凝组为435.2±424.7 mL,差异有统计学意义。关于术后肝功能,大多数实验室数据根据凝血装置显示无显著差异。术后并发症发生率无显著差异。
显然,这种新的软凝装置是一种在不阻断血流情况下进行供体肝实质横断的安全可行技术。