Sato Ryo, Ichiyasu Hidenori, Saeki Sho, Sakata Shinya, Sasaki Ji-ichirou, Fujii Kazuhiko, Saita Naoki, Kohrogi Hirotsugu
Department of Respiratory Medicine, Kumamoto University Hospital, Japan.
Intern Med. 2012;51(14):1909-12. doi: 10.2169/internalmedicine.51.7330. Epub 2012 Jul 15.
Non-small cell lung cancer was metastasized at the septal side of right atrium in 59-year-old woman who had undergone surgery for lung cancer 11 years ago. The cardiac metastasis was found by whole-body 18F-fluoro-deoxy-glucose positron emission tomography/computed tomography (FDG-PET/CT), and cytologically confirmed by myocardial aspiration biopsy with right heart catheterization. The patient was treated with 4 cycles of carboplatin/pemetrexed followed by maintenance therapy with pemetrexed. The metastatic cardiac tumor shrank, and the atrioventricular (AV) block in ECG was improved. In this case, FDG-PET and chemotherapy were valuable for diagnosis and treatment of cardiac metastasis from non-small cell lung cancer.
一名59岁女性11年前接受过肺癌手术，非小细胞肺癌转移至右心房间隔侧。通过全身18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（FDG-PET/CT）发现心脏转移，并通过右心导管心肌穿刺活检进行细胞学确诊。该患者接受了4个周期的卡铂/培美曲塞治疗，随后接受培美曲塞维持治疗。转移性心脏肿瘤缩小，心电图中的房室传导阻滞得到改善。在这种情况下，FDG-PET和化疗对非小细胞肺癌心脏转移的诊断和治疗具有重要价值。
