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肺趋化性分枝杆菌病在克拉霉素和左氧氟沙星联合治疗后显示出临床改善。

Pulmonary Mycobacterium kyorinense disease showed clinical improvement following combined therapy with clarithromycin and levofloxacin.

作者信息

Kobashi Yoshihiro, Mouri Keiji, Obase Yasushi, Kato Shigeki, Oka Mikio

机构信息

Division of Respiratory Diseases, Department of Medicine, Kawasaki Medical School, Japan.

出版信息

Intern Med. 2012;51(14):1923-6. doi: 10.2169/internalmedicine.51.6431. Epub 2012 Jul 15.

DOI:10.2169/internalmedicine.51.6431
PMID:22821114
Abstract

A 63-year-old man with a past history of resection of pulmonary adenocarcinoma and COPD visited our hospital because of fever, cough and purulent sputum. Chest CT showed an infiltration shadow with multiple bullae in the right lung. There was a slight elevation of the inflammatory response. We established a definitive diagnosis by frequent isolation of Mycobacterium kyorinense on a sputum culture test of acid-fast bacilli. Clarithromycin and levofloxacin were administered after identification of M. kyorinense using a 16S rRNA gene sequence. Subsequently his symptoms improved following combined therapy with clarithromycin and levofloxacin.

摘要

一名63岁男性,既往有肺腺癌切除病史及慢性阻塞性肺疾病(COPD),因发热、咳嗽和脓性痰前来我院就诊。胸部CT显示右肺有浸润影伴多发肺大疱。炎症反应略有升高。通过在抗酸杆菌痰培养试验中频繁分离出京都分枝杆菌,我们确立了明确诊断。在使用16S rRNA基因序列鉴定出京都分枝杆菌后,给予克拉霉素和左氧氟沙星治疗。随后,在克拉霉素和左氧氟沙星联合治疗后,他的症状有所改善。

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