Department of Anesthesiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.
Curr Opin Anaesthesiol. 2012 Oct;25(5):556-62. doi: 10.1097/ACO.0b013e328357225c.
Prehospital management affects long-term outcome of patients with severe traumatic brain injury (TBI). This article reviews the current concepts and ongoing controversies of prehospital treatment of severe TBI.
Prehospital management focuses on the prevention of secondary brain injury and rapid transport to a neurotrauma center for definitive diagnosis and life- as well as brain-saving emergency treatment such as decompressive craniotomy. There is a broad consensus that adequate airway management, prevention of hypoxia, hypocapnia or hypercapnia, prevention of hypotension and control of hemorrhage represent preclinical therapeutic modalities that may contribute to improved survival in severe TBI. The precise role of prehospital endotracheal intubation, osmotic agents and early therapeutic hypothermia needs to be clarified in the context of time required for transportation, local infrastructure, geographical factors and availability of experienced emergency teams.
Prehospital management of TBI remains challenging. There are no universal objectives suitable to all patients. Randomized, controlled clinical trials are necessary for developing optimal protocols for paramedic and physician emergency medical teams.
院前管理会影响严重创伤性脑损伤(TBI)患者的长期预后。本文综述了严重 TBI 的院前治疗的当前概念和持续存在的争议。
院前管理侧重于预防继发性脑损伤,并迅速将患者转运至神经创伤中心,以进行明确诊断和进行挽救生命及脑功能的紧急治疗,例如减压性颅骨切开术。人们广泛认为,充分的气道管理、预防缺氧、低碳酸血症或高碳酸血症、预防低血压和控制出血是可能有助于改善严重 TBI 患者生存率的临床前治疗方法。在需要转运的时间、当地基础设施、地理因素和有经验的急救团队的可用性的背景下,需要阐明院前气管插管、渗透性药物和早期治疗性低温的精确作用。
TBI 的院前管理仍然具有挑战性。没有适用于所有患者的通用目标。有必要开展随机对照临床试验,为护理人员和医生的急诊医疗团队制定最佳方案。