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现场格拉斯哥昏迷评分 < 9 的小儿患者插管的观察死亡率与预期死亡率。

Observed versus expected mortality in pediatric patients intubated in the field with Glasgow Coma Scale scores < 9.

机构信息

Department of Neurosurgery, University Medical Center Hamburg-Eppendorf (UKE), Martinistrasse 52, 20246, Hamburg, Germany.

Department of Trauma, Hand and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.

出版信息

Eur J Trauma Emerg Surg. 2019 Oct;45(5):769-776. doi: 10.1007/s00068-018-01065-2. Epub 2019 Jan 10.

Abstract

PURPOSE

A Glasgow Coma Scale (GCS) score of 8 or less in patients suffering from severe traumatic brain injury (TBI) represents a decision-making marker in terms of intubation. This study evaluated the impact of prehospital intubation on the mortality of these TBI cases among different age groups.

METHODS

This study included the data from patients predominantly suffering from severe TBI [Abbreviated Injury Scale (AIS) of the head ≥ 3, GCS score < 9, Injury Severity Score (ISS) > 9] who were registered in TraumaRegister DGU from 2002 to 2013. An age-related analysis of five subgroups was performed (1-6, 7-15, 16-55, 56-79, and ≥ 80 years old). The observed and expected mortality were matched according to the Revised Injury Severity Classification, version II.

RESULTS

A total of 21,242 patients were included. More often, the intubated patients were severely injured when compared to the non-intubated patients (median ISS 29, IQR 22-41 vs. 24, IQR 16-29, respectively), with an associated higher mortality (42.2% vs. 30.0%, respectively). When compared to the calculated expected mortality, the observed mortality was significantly higher among the intubated patients within the youngest subgroup (42.2% vs. 33.4%, respectively; p = 0.03).

CONCLUSIONS

The observed mortality in the intubated children 1-6 years old suffering from severe TBI seemed to be higher than expected. Whether or not a GCS score of 8 or less is the only reliable criterion for intubation in this age group should be investigated in further trials.

摘要

目的

对于患有严重创伤性脑损伤(TBI)的患者,如果格拉斯哥昏迷评分(GCS)为 8 或更低,则表示需要进行插管决策。本研究评估了院前插管对不同年龄组 TBI 患者死亡率的影响。

方法

本研究纳入了 2002 年至 2013 年期间创伤登记处 DGU 登记的主要患有严重 TBI(头部损伤严重程度评分(AIS)≥3、GCS 评分<9、损伤严重程度评分(ISS)>9)的患者数据。对五个年龄亚组(1-6 岁、7-15 岁、16-55 岁、56-79 岁和≥80 岁)进行了年龄相关性分析。根据修订后的损伤严重程度分类,版本 II,观察到的和预期的死亡率相匹配。

结果

共纳入 21242 例患者。与未插管患者相比,插管患者的损伤更严重(中位数 ISS 29,四分位距 22-41 与 24,四分位距 16-29),死亡率也更高(分别为 42.2%和 30.0%)。与计算的预期死亡率相比,插管患者在年龄最小的亚组(1-6 岁)中观察到的死亡率明显更高(分别为 42.2%和 33.4%;p=0.03)。

结论

接受严重 TBI 治疗的 1-6 岁插管儿童的观察死亡率似乎高于预期。在这个年龄组,GCS 评分是否为 8 或更低是插管的唯一可靠标准,应在进一步的试验中进行调查。

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