1-芳基偶氮-3,4,6,7,8,9-六氢喹嗪的制备及其抗菌活性
Preparation and antimicrobial activity of 1-arylazo-3,4,6,7,8,9-hexahydroquinolizines.
作者信息
Sparatore A, Boido C C, Boido V, Sparatore F, Debbia E, Schito A P
机构信息
Istituto Chimico Farmaceutico, Università di Milano, Italy.
出版信息
Farmaco. 1990 Jul;45(7-8):867-77.
PMID:2282120
Abstract
A set of 1-(R-arylazo)-3,4,6,7,8,9-hexahydroquinolizines, bearing different substituents on the benzene ring, were prepared and tested for antimicrobial activity. These compounds exhibit only a very weak activity against gram-positive and gram-negative bacteria, but are fairly active against several Candida species and other yeast-like fungi.
摘要
制备了一组在苯环上带有不同取代基的1-（R-芳基偶氮）-3,4,6,7,8,9-六氢喹嗪，并对其抗菌活性进行了测试。这些化合物对革兰氏阳性菌和革兰氏阴性菌仅表现出非常微弱的活性，但对几种念珠菌属和其他酵母样真菌具有相当的活性。
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