Department of General Surgery, Singapore General Hospital, Singapore.
Ann Acad Med Singap. 2012 Jun;41(6):247-51.
Male breast cancer is a rare disease entity, with little data from the Southeast Asian perspective. Hence, this study aims to review the data from our local experience in order to better delineate the disease characteristics in our population.
Male patients with histologically proven breast cancer were identified from a prospectively collected database. The clinical, histopathological and survival data were reviewed retrospectively and analysed.
Twenty-one patients were identified. The median age at diagnosis was 68 years. Eighteen patients underwent simple mastectomy with curative intent, with the remaining patients having metastatic disease at presentation. Almost half of the patients presented with stage III or IV disease. At the time of analysis, median overall survival was 50 months and median disease-free survival was 47.5 months. None of the patients had any documented family history or risk factors for male breast cancer.
The disease appears to be a sporadic and rare occurrence in the local male population. A high index of suspicion should be maintained in males presented with a unilateral breast lump so that appropriate treatment can be instituted.
男性乳腺癌是一种罕见的疾病实体，来自东南亚的相关数据较少。因此，本研究旨在回顾我们的本地经验数据，以便更好地描绘我们人群中的疾病特征。
从一个前瞻性收集的数据库中确定了经组织学证实的男性乳腺癌患者。回顾性地审查和分析了临床、组织病理学和生存数据。
共确定了 21 名患者。诊断时的中位年龄为 68 岁。18 名患者接受了单纯乳房切除术以达到治愈目的，其余患者在就诊时患有转移性疾病。几乎一半的患者处于 III 期或 IV 期。在分析时，中位总生存期为 50 个月，中位无病生存期为 47.5 个月。没有患者有男性乳腺癌的任何记录家族史或风险因素。
在当地男性人群中，这种疾病似乎是一种偶发的罕见疾病。对于出现单侧乳房肿块的男性，应保持高度怀疑，以便进行适当的治疗。
