Cincinnati VA Medical Center, PTSD & Anxiety Disorders Clinic, Cincinnati, OH 45220, USA.
J Trauma Stress. 2012 Aug;25(4):426-32. doi: 10.1002/jts.21722. Epub 2012 Jul 20.
Among military personnel, posttraumatic stress disorder (PTSD), major depressive disorder (MDD), and a history of traumatic brain injury (TBI) are frequently reported, highlighting the need for treatment outcome research with this population. This study examined the influence of the presence or absence of comorbid MDD on the outcome of a residential treatment program at the midpoint and end of the program for 47 male veterans with PTSD and a history of TBI. Results demonstrated significant decreases of self-reported symptoms on the PTSD Checklist-Stressor Specific Version (PCL-S; MDD, d = 1.19; No MDD, d = 1.17) and the Beck Depression Inventory-II (BDI-II; MDD, d = 0.98; No MDD, d = 1.09) following treatment for both groups. There were no differences in the rate of symptom reduction between groups. Individuals who also met criteria for MDD at pretreatment, however, evidenced higher scores on symptom measures at all assessment time points (ds = 0.60-1.25).
在军人中，创伤后应激障碍（PTSD）、重度抑郁障碍（MDD）和创伤性脑损伤（TBI）的病史经常被报道，这突出了需要对这一人群进行治疗结果研究。本研究调查了共病 MDD 的存在与否对 PTSD 和 TBI 病史的 47 名男性退伍军人在住宅治疗计划中点和计划结束时的治疗结果的影响。结果表明，两组患者的 PTSD 检查表-应激特异性版本（PCL-S；MDD，d = 1.19；无 MDD，d = 1.17）和贝克抑郁量表-第二版（BDI-II；MDD，d = 0.98；无 MDD，d = 1.09）的自我报告症状均显著降低。两组之间的症状缓解率没有差异。然而，在治疗前也符合 MDD 标准的个体在所有评估时间点的症状测量中得分更高（ds = 0.60-1.25）。
