Donald P J
Otolaryngol Head Neck Surg (1979). 1979 Jan-Feb;87(1):42-6. doi: 10.1177/019459987908700112.
Malignant degeneration in a juvenile nasopharyngeal angiofibroma has been reported in the literature in only four patients. All of these persons had been previously treated for cure with gamma irradiation. The case report of a 47-year-old man with a 31-year history of nasal obstruction is presented. A recurrence excised 18 months after initial removal of an angiofibroma revealed the surprising diagnosis of fibrosarcoma.
文献中仅报道过4例青少年鼻咽血管纤维瘤发生恶性变的病例。所有这些患者此前均接受过伽马射线放射治疗以达治愈目的。本文报告了一名47岁男性患者，其有31年鼻塞病史。在最初切除血管纤维瘤18个月后复发的肿物经切除，病理结果令人惊讶地诊断为纤维肉瘤。
